{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Haskett DG"],"funding":["NIBIB NIH HHS","NHLBI NIH HHS"],"pagination":["1814-1822.e3"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6200342"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["156(5)"],"pubmed_abstract":["<h4>Objective</h4>Tissue-engineered vascular grafts containing adipose-derived mesenchymal stem cells offer an alternative to small-diameter vascular grafts currently used in cardiac and lower-extremity revascularization procedures. Adipose-derived, mesenchymal stem cell-infused, tissue-engineered vascular grafts have been shown to promote remodeling and vascular homeostasis in vivo and offer a possible treatment solution for those with cardiovascular disease. Unfortunately, the time needed to cultivate adipose-derived mesenchymal stem cells remains a large hurdle for tissue-engineered vascular grafts as a treatment option. The purpose of this study was to determine if stromal vascular fraction (known to contain progenitor cells) seeded tissue-engineered vascular grafts would remain patent"],"journal":["The Journal of thoracic and cardiovascular surgery"],"pubmed_title":["An exploratory study on the preparation and evaluation of a \"same-day\" adipose stem cell-based tissue-engineered vascular graft."],"pmcid":["PMC6200342"],"funding_grant_id":["T32 HL098036","R21 EB016138","R01 HL130077","R21 HL130784"],"pubmed_authors":["Luketich SK","Kokai LE","Wagner WR","Haskett DG","D'Amore A","Lorentz KL","Josowitz AD","Rubin JP","Marra KG","Vorp DA","Saleh KS","Weinbaum JS"],"additional_accession":[]},"is_claimable":false,"name":"An exploratory study on the preparation and evaluation of a \"same-day\" adipose stem cell-based tissue-engineered vascular graft.","description":"<h4>Objective</h4>Tissue-engineered vascular grafts containing adipose-derived mesenchymal stem cells offer an alternative to small-diameter vascular grafts currently used in cardiac and lower-extremity revascularization procedures. Adipose-derived, mesenchymal stem cell-infused, tissue-engineered vascular grafts have been shown to promote remodeling and vascular homeostasis in vivo and offer a possible treatment solution for those with cardiovascular disease. Unfortunately, the time needed to cultivate adipose-derived mesenchymal stem cells remains a large hurdle for tissue-engineered vascular grafts as a treatment option. The purpose of this study was to determine if stromal vascular fraction (known to contain progenitor cells) seeded tissue-engineered vascular grafts would remain patent","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Nov","modification":"2025-04-04T13:30:19.813Z","creation":"2019-11-07T08:01:44Z"},"accession":"S-EPMC6200342","cross_references":{"pubmed":["30057192"],"doi":["10.1016/j.jtcvs.2018.05.120"]}}