biostudies-literatureSamson JNCRR NIH HHS339-44https://www.ebi.ac.uk/biostudies/studies/S-EPMC6201687biostudies-literatureUnknown3(2)A new method for synthesizing gold, nickel, and cobalt metal nanoparticles at room temperature from metal salts employing plasmid DNA in a toroidal topology as a sacrificial mold is presented. The diameter of the toroidal DNA drives the formation and size of the nanoparticle, and UV light initiates the oxidation of the DNA and concomitant reduction of the DNA bound metal ions. The nanoparticles were characterized by atomic force microscopy (AFM), transmission electron microscopy (TEM), and electron diffraction (ED).ACS nanoFabrication of metal nanoparticles using toroidal plasmid DNA as a sacrificial mold.PMC6201687G12-RR-03037G12 RR003037Varotto ANahirney PCDrain CMPiscopo IToschi ASamson JfalseFabrication of metal nanoparticles using toroidal plasmid DNA as a sacrificial mold.A new method for synthesizing gold, nickel, and cobalt metal nanoparticles at room temperature from metal salts employing plasmid DNA in a toroidal topology as a sacrificial mold is presented. The diameter of the toroidal DNA drives the formation and size of the nanoparticle, and UV light initiates the oxidation of the DNA and concomitant reduction of the DNA bound metal ions. The nanoparticles were characterized by atomic force microscopy (AFM), transmission electron microscopy (TEM), and electron diffraction (ED).2009-01-01T00:00:00Z2009 Feb2020-10-29T13:39:15Z2019-03-27T00:04:21ZS-EPMC62016871923606910.1021/nn800758n