biostudies-literatureMendizabal BNCATS NIH HHSNIDDK NIH HHS625-631https://www.ebi.ac.uk/biostudies/studies/S-EPMC6202222biostudies-literatureUnknown72(3)Although hypertension is identifiable in children and adolescents, there are many knowledge gaps on how to best define and manage high blood pressure in the young. SHIP-AHOY (Study of High Blood Pressure in Pediatrics: Adult Hypertension Onset in Youth) is being conducted to address these knowledge gaps. Five hundred adolescents will be recruited and will undergo ambulatory blood pressure monitoring, echocardiographic, vascular, and cognitive assessments, as well as epigenetic studies to identify mechanisms that underlie the development of hypertensive target organ damage. Details of the design and methods that will be utilized in SHIP-AHOY are presented here, as well as baseline characteristics of the first 264 study participants. The primary aim of the study is to develop a risk-based definition of hypertension in the young that will result in better understanding of the transition from blood pressure in youth to adult cardiovascular disease.Hypertension (Dallas, Tex. : 1979)SHIP-AHOY (Study of High Blood Pressure in Pediatrics: Adult Hypertension Onset in Youth).PMC6202222UL1 TR001425T35 DK060444UL1 TR002319Rosner BMitsnefes MBecker RHanevold CDMendizabal BDaniels SRHamdani GSamuels JAFalkner BEUrbina EMIngelfinger JRMartin LJFlynn JTLande MHooper SRMeyers KfalseSHIP-AHOY (Study of High Blood Pressure in Pediatrics: Adult Hypertension Onset in Youth).Although hypertension is identifiable in children and adolescents, there are many knowledge gaps on how to best define and manage high blood pressure in the young. SHIP-AHOY (Study of High Blood Pressure in Pediatrics: Adult Hypertension Onset in Youth) is being conducted to address these knowledge gaps. Five hundred adolescents will be recruited and will undergo ambulatory blood pressure monitoring, echocardiographic, vascular, and cognitive assessments, as well as epigenetic studies to identify mechanisms that underlie the development of hypertensive target organ damage. Details of the design and methods that will be utilized in SHIP-AHOY are presented here, as well as baseline characteristics of the first 264 study participants. The primary aim of the study is to develop a risk-based definition of hypertension in the young that will result in better understanding of the transition from blood pressure in youth to adult cardiovascular disease.2018-01-01T00:00:00Z2018 Sep2024-11-09T15:48:44.885Z2019-09-04T07:03:00ZS-EPMC62022222998710210.1161/HYPERTENSIONAHA.118.1143410.1161/hypertensionaha.118.11434