{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Putcha N"],"funding":["NHLBI NIH HHS"],"pagination":["710-717"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6207135"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(6)"],"pubmed_abstract":["<h4>Rationale</h4>Chronic obstructive pulmonary disease (COPD) is a common cause of morbidity and associated with a significant burden of comorbidities. Although anemia is associated with adverse outcomes in COPD, its contribution to outcomes in individuals with other comorbid chronic diseases is not well understood.<h4>Objectives</h4>This study examines the association of anemia with outcomes in a large, well-characterized COPD cohort, and attempts to understand the contribution of anemia to outcomes and phenotypes in individuals with other comorbidities.<h4>Methods</h4>Participants with COPD from SPIROMICS (the Subpopulations and Intermediate Outcome Measures in COPD Study) were analyzed in adjusted models to determine the associations of normocytic anemia with clinical outcomes, compute"],"journal":["Annals of the American Thoracic Society"],"pubmed_title":["Anemia and Adverse Outcomes in a Chronic Obstructive Pulmonary Disease Population with a High Burden of Comorbidities. An Analysis from SPIROMICS."],"pmcid":["PMC6207135"],"funding_grant_id":["R01 HL124099","U01 HL137880","HHSN268200900015C","HHSN268200900016C","HHSN268200900017C","HHSN268200900018C","HHSN268200900019C","HHSN268200900009C","U24 HL141762","HHSN268200900020C","K23 HL130627","HHSN268200900013C","HHSN268200900014C","K23 HL123594"],"pubmed_authors":["Krishnan JA","Paul GG","Hansel NN","Anderson WH","Kleerup EC","Oelsner EC","GmbH N","Labaki WW","Bowler RP","Putcha N","Alexis NE","Christenson SA","Comellas AP","Woo J","Doerschuk CM","Graham Barr R","Carretta EE","Cooper CB","Newell JD","Lazarus SC","Woodruff PG","Wells JM","Couper DJ","Freeman CM","Tashkin DP","Martinez C","Sidhaye VK","Paulin LM","Robert Paine","Barr RG","Scholand MB","O'Neal WK","Han MK","Croxton T","Postow L","Kanner RE","Criner GJ","Hoffman EA","LaVange LM","Hastie AT","Fawzy A","Martinez FJ","Boucher RC","SPIROMICS investigators","Curtis JL","Bleecker ER","Wise RA","Meyers DA","Lambert AA","Crystal RG","Dransfield MT","Psoter KJ","Rennard SI","Kaner RJ"],"additional_accession":[]},"is_claimable":false,"name":"Anemia and Adverse Outcomes in a Chronic Obstructive Pulmonary Disease Population with a High Burden of Comorbidities. An Analysis from SPIROMICS.","description":"<h4>Rationale</h4>Chronic obstructive pulmonary disease (COPD) is a common cause of morbidity and associated with a significant burden of comorbidities. Although anemia is associated with adverse outcomes in COPD, its contribution to outcomes in individuals with other comorbid chronic diseases is not well understood.<h4>Objectives</h4>This study examines the association of anemia with outcomes in a large, well-characterized COPD cohort, and attempts to understand the contribution of anemia to outcomes and phenotypes in individuals with other comorbidities.<h4>Methods</h4>Participants with COPD from SPIROMICS (the Subpopulations and Intermediate Outcome Measures in COPD Study) were analyzed in adjusted models to determine the associations of normocytic anemia with clinical outcomes, compute","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Jun","modification":"2026-05-01T21:11:46.671Z","creation":"2019-07-01T13:50:37Z"},"accession":"S-EPMC6207135","cross_references":{"pubmed":["30726108"],"doi":["10.1513/annalsats.201708-687oc","10.1513/AnnalsATS.201708-687OC"]}}