biostudies-literatureUnknown23(10)Sutradhar MFundação para a Ciência e a Tecnologia, PortugalBis(2-hydroxybenzylidene)isophthalohydrazide (H?L) has been used to synthesize the dinuclear [Cu?(1?<i>NO</i>²:2?<i>N'O'</i>²-H?L)(NO?)?(H?O)?] (<b>1</b>) and the tetranuclear [Cu?(?-1?<i>NO</i>²:2?<i>N</i><i>'O</i>²-H?L)?(?-NO?)?(H?O)?]·2C?H?OH (<b>2</b>) complexes. The solvent plays an important role in determining the ligand behaviour in the syntheses of the complexes. An ethanol-acetonitrile mixture of solvents favours partials enolization in the case of <b>2</b>. Both complexes have been characterized by elemental analysis, infrared radiation (IR), single crystal X-ray crystallography and electrochemical methods. The variable temperature magnetic susceptibility measurements of <b>2</b> show strong antiferromagnetic coupling between the central nitrato-bridged Cu (II) ions. The catalytic activity of both <b>1</b> and <b>2</b> has been screened toward the solvent-free microwave-assisted oxidation of alcohols and the peroxidative oxidation of alkanes under mild conditions. Complex <b>1</b> exhibits the highest activity for both oxidation reactions, leading selectively to a maximum product yield of 99% (for the 1-phenylethanol oxidation after 1 h without any additive) and 13% (for the cyclohexane oxidation to cyclohexyl hydroperoxide, cyclohexanol and cyclohexanone after 3 h).Molecules (Basel, Switzerland)https://www.ebi.ac.uk/biostudies/studies/S-EPMC6222479biostudies-literaturePeroxidative Oxidation of Alkanes and Alcohols under Mild Conditions by Di- and Tetranuclear Copper (II) Complexes of Bis (2-Hydroxybenzylidene) Isophthalohydrazide.PMC6222479UID/QUI/00100/2013, PTDC/QEQ-ERQ/1648/2014, PTDC/QEQ-QIN/3967/2014 and SFRH/BPD/86067/2012Sutradhar MGuedes da Silva MFCAlegria ECBAPombeiro AJLLiu CMfalsePeroxidative Oxidation of Alkanes and Alcohols under Mild Conditions by Di- and Tetranuclear Copper (II) Complexes of Bis (2-Hydroxybenzylidene) Isophthalohydrazide.Bis(2-hydroxybenzylidene)isophthalohydrazide (H?L) has been used to synthesize the dinuclear [Cu?(1?<i>NO</i>²:2?<i>N'O'</i>²-H?L)(NO?)?(H?O)?] (<b>1</b>) and the tetranuclear [Cu?(?-1?<i>NO</i>²:2?<i>N</i><i>'O</i>²-H?L)?(?-NO?)?(H?O)?]·2C?H?OH (<b>2</b>) complexes. The solvent plays an important role in determining the ligand behaviour in the syntheses of the complexes. An ethanol-acetonitrile mixture of solvents favours partials enolization in the case of <b>2</b>. Both complexes have been characterized by elemental analysis, infrared radiation (IR), single crystal X-ray crystallography and electrochemical methods. The variable temperature magnetic susceptibility measurements of <b>2</b> show strong antiferromagnetic coupling between the central nitrato-bridged Cu (II) ions. The catalytic activity of both <b>1</b> and <b>2</b> has been screened toward the solvent-free microwave-assisted oxidation of alcohols and the peroxidative oxidation of alkanes under mild conditions. Complex <b>1</b> exhibits the highest activity for both oxidation reactions, leading selectively to a maximum product yield of 99% (for the 1-phenylethanol oxidation after 1 h without any additive) and 13% (for the cyclohexane oxidation to cyclohexyl hydroperoxide, cyclohexanol and cyclohexanone after 3 h).2018-01-01T00:00:00Z2018 Oct2021-02-21T08:14:34Z2019-03-27T00:06:52ZS-EPMC62224793034772310.3390/molecules23102699