biostudies-literatureGopalakrishnan SCarlsbergfondetMINECO/FEDERHoward Hughes Medical InstituteNSFCAage og Johanne Louis-Hansens FondNIMH NIH HHSThe Velux FoundationsNIMHEuropean Research CouncilMarie Skłodowska-CurieSecretaria d’Universitats i Recerca and CERCAUniversities of Oslo and CopenhagenLundbeckfondenObra Social “La Caixa,”Danish National Research Foundation3441-3449.e5https://www.ebi.ac.uk/biostudies/studies/S-EPMC6224481biostudies-literatureUnknown28(21)The evolutionary history of the wolf-like canids of the genus Canis has been heavily debated, especially regarding the number of distinct species and their relationships at the population and species level [1-6]. We assembled a dataset of 48 resequenced genomes spanning all members of the genus Canis except the black-backed and side-striped jackals, encompassing the global diversity of seven extant canid lineages. This includes eight new genomes, including the first resequenced Ethiopian wolf (Canis simensis), one dhole (Cuon alpinus), two East African hunting dogs (Lycaon pictus), two Eurasian golden jackals (Canis aureus), and two Middle Eastern gray wolves (Canis lupus). The relationships between the Ethiopian wolf, African golden wolf, and golden jackal were resolved. We highlight the Current biology : CBInterspecific Gene Flow Shaped the Evolution of the Genus Canis.PMC6224481681396655732-WhereWolf91531303DNRF94U01 MH106874681396-Extinction GenomicsBFU2017-86471-P676154-ArchSci2020CF14–0995R52–5062Koepfli KPBachmann LMirarab SMontero MMPetersen BWiig OSerres ALiu YHGonzalez-Basallote VMKuderna LRueness EKHansen AJRamos-Madrigal JBudd JGopalakrishnan SMarques-Bonet TSinding MSHeide-Jorgensen MPCaroe CSamaniego Castruita JAFernandes CSillero CSicheritz-Ponten TGaubert PVieira FGGilbert MTPWang GDNiemann JfalseInterspecific Gene Flow Shaped the Evolution of the Genus Canis.The evolutionary history of the wolf-like canids of the genus Canis has been heavily debated, especially regarding the number of distinct species and their relationships at the population and species level [1-6]. We assembled a dataset of 48 resequenced genomes spanning all members of the genus Canis except the black-backed and side-striped jackals, encompassing the global diversity of seven extant canid lineages. This includes eight new genomes, including the first resequenced Ethiopian wolf (Canis simensis), one dhole (Cuon alpinus), two East African hunting dogs (Lycaon pictus), two Eurasian golden jackals (Canis aureus), and two Middle Eastern gray wolves (Canis lupus). The relationships between the Ethiopian wolf, African golden wolf, and golden jackal were resolved. We highlight the 2018-01-01T00:00:00Z2018 Nov2026-04-29T09:59:22.077Z2019-03-27T00:07:15ZS-EPMC62244813034412010.1016/j.cub.2018.08.041