{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Khan SS"],"funding":["NCATS NIH HHS","NIDDK NIH HHS","Kaiser Foundation Research Institute","NHLBI NIH HHS","University of Alabama at Birmingham","National Heart, Lung, and Blood Institute","Northwestern University","University of Minnesota","National Institutes of Health","Johns Hopkins University School of Medicine"],"pagination":["1261-1269.e8"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6286208"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["31(12)"],"pubmed_abstract":["Background
The aim of this study was to determine whether long-term patterns of change in adiposity throughout young adulthood are associated with systolic and diastolic function in midlife.Methods
Participants in the Coronary Artery Risk Development in Young Adults study, a multicenter, population-based cohort, underwent repeated anthropometric assessment (body mass index [BMI], waist circumference, and waist-to-hip ratio) from examination years 0 to 25. At year 25, longitudinal, circumferential, and radial strain and tissue Doppler velocities were assessed by echocardiography. Group-based trajectory modeling was used to identify 25-year trajectories of change in anthropometric measures and to examine associations between trajectories of adiposity change and indices of car"],"journal":["Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography"],"pubmed_title":["Association of Patterns of Change in Adiposity With Diastolic Function and Systolic Myocardial Mechanics From Early Adulthood to Middle Age: The Coronary Artery Risk Development in Young Adults Study."],"pmcid":["PMC6286208"],"funding_grant_id":["HHSN268200900041C","HHSN268201300028C","HHSN268201300027C","KL2TR001424","F32 HL129695","P30 DK079626","HHSN268201300029C","HHSN268201300025C","F32HL129695","KL2 TR001424"],"pubmed_authors":["Panjwani A","Lewis CE","Khan SS","Liu K","Goff DC","Reis J","Vasconcellos HD","Allen NB","Lima JAC","Colangelo LA","Lloyd-Jones D","Shay CM","Shah SJ"],"additional_accession":[]},"is_claimable":false,"name":"Association of Patterns of Change in Adiposity With Diastolic Function and Systolic Myocardial Mechanics From Early Adulthood to Middle Age: The Coronary Artery Risk Development in Young Adults Study.","description":"Background
The aim of this study was to determine whether long-term patterns of change in adiposity throughout young adulthood are associated with systolic and diastolic function in midlife.Methods
Participants in the Coronary Artery Risk Development in Young Adults study, a multicenter, population-based cohort, underwent repeated anthropometric assessment (body mass index [BMI], waist circumference, and waist-to-hip ratio) from examination years 0 to 25. At year 25, longitudinal, circumferential, and radial strain and tissue Doppler velocities were assessed by echocardiography. Group-based trajectory modeling was used to identify 25-year trajectories of change in anthropometric measures and to examine associations between trajectories of adiposity change and indices of car","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Dec","modification":"2025-04-04T01:57:49.49Z","creation":"2020-10-29T14:39:39Z"},"accession":"S-EPMC6286208","cross_references":{"pubmed":["30181008"],"doi":["10.1016/j.echo.2018.07.014"]}}