biostudies-literatureVerfurden MLEconomic and Social Research CouncilMedical Research CouncilNational Institute for Health Research (NIHR)1125-1131https://www.ebi.ac.uk/biostudies/studies/S-EPMC6287561biostudies-literatureUnknown103(12)<h4>Objective</h4>To determine the risk of death from two potentially avoidable causes with different aetiologies: respiratory tract infection (RTI) and sudden unexplained death (SUD) in children with and without chronic conditions.<h4>Design</h4>Whole-country, birth cohort study using linked administrative health databases from Scotland.<h4>Setting and participants</h4>Children aged 2 months to less than 5 years in Scotland between 2000 and 2014.<h4>Main outcome measures</h4>Relative risk of death (expressed as the HR) related to RTIs or SUD, in children with and without chronic conditions. We separately analysed deaths at ages 2-11 months and at 1-4 years and adjusted for birth characteristics, socioeconomic status and vaccination uptake using Cox regression.<h4>Results</h4>The cohort coArchives of disease in childhoodAvoidable mortality from respiratory tract infection and sudden unexplained death in children with chronic conditions: a data linkage study.PMC6287561NF-SI-0513-10046PDF-2013-06-004109/0001ES/L007517/1HDR-2008NF-SI-0616-10097HDR-9006HDR-9003Verfurden MLSebire NGilbert RHardelid PfalseAvoidable mortality from respiratory tract infection and sudden unexplained death in children with chronic conditions: a data linkage study.<h4>Objective</h4>To determine the risk of death from two potentially avoidable causes with different aetiologies: respiratory tract infection (RTI) and sudden unexplained death (SUD) in children with and without chronic conditions.<h4>Design</h4>Whole-country, birth cohort study using linked administrative health databases from Scotland.<h4>Setting and participants</h4>Children aged 2 months to less than 5 years in Scotland between 2000 and 2014.<h4>Main outcome measures</h4>Relative risk of death (expressed as the HR) related to RTIs or SUD, in children with and without chronic conditions. We separately analysed deaths at ages 2-11 months and at 1-4 years and adjusted for birth characteristics, socioeconomic status and vaccination uptake using Cox regression.<h4>Results</h4>The cohort co2018-01-01T00:00:00Z2018 Dec2026-07-16T15:16:44.437Z2026-07-11T03:06:36.106ZS-EPMC62875613000794510.1136/archdischild-2017-314098