{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Garg P"],"funding":["British Heart Foundation","Dutch ZonMw","National Institute for Health Research (NIHR)","ZonMw"],"pagination":["108-117"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6302263"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(1)"],"pubmed_abstract":["Aims
The main aim of this study was to characterize changes in the left ventricular (LV) blood flow kinetic energy (KE) using four-dimensional (4D) flow cardiovascular magnetic resonance imaging (CMR) in patients with myocardial infarction (MI) with/without LV thrombus (LVT).Methods and results
This is a prospective cohort study of 108 subjects [controls = 40, MI patients without LVT (LVT- = 36), and MI patients with LVT (LVT+ = 32)]. All underwent CMR including whole-heart 4D flow. LV blood flow KE wall calculated using the formula: KE=12 ρblood . Vvoxel . v2, where ρ = density, V = volume, v = velocity, and was indexed to LV end-diastolic volume. Patient with MI had significantly lower LV KE components than controls (P < 0.05). LVT+ and LVT- patients had comparable infarc"],"journal":["European heart journal. Cardiovascular Imaging"],"pubmed_title":["Left ventricular thrombus formation in myocardial infarction is associated with altered left ventricular blood flow energetics."],"pmcid":["PMC6302263"],"funding_grant_id":["CL-2017-02-002","104003001","FS/10/62/28409"],"pubmed_authors":["Dobson LE","Bissell M","Vijayan S","van der Geest RJ","Greenwood JP","Brown LAE","Garg P","Al Musa T","Fent GJ","Crandon S","Hassell MECJ","Westenberg JJM","Foley JRJ","Swoboda PP","Onciul S","Nijveldt R","Elbaz MSM","Chew PG","Dall'Armellina E","Plein S"],"additional_accession":[]},"is_claimable":false,"name":"Left ventricular thrombus formation in myocardial infarction is associated with altered left ventricular blood flow energetics.","description":"Aims
The main aim of this study was to characterize changes in the left ventricular (LV) blood flow kinetic energy (KE) using four-dimensional (4D) flow cardiovascular magnetic resonance imaging (CMR) in patients with myocardial infarction (MI) with/without LV thrombus (LVT).Methods and results
This is a prospective cohort study of 108 subjects [controls = 40, MI patients without LVT (LVT- = 36), and MI patients with LVT (LVT+ = 32)]. All underwent CMR including whole-heart 4D flow. LV blood flow KE wall calculated using the formula: KE=12 ρblood . Vvoxel . v2, where ρ = density, V = volume, v = velocity, and was indexed to LV end-diastolic volume. Patient with MI had significantly lower LV KE components than controls (P < 0.05). LVT+ and LVT- patients had comparable infarc","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Jan","modification":"2025-04-04T13:07:39.997Z","creation":"2019-03-27T00:14:34Z"},"accession":"S-EPMC6302263","cross_references":{"pubmed":["30137274"],"doi":["10.1093/ehjci/jey121"]}}