biostudies-literatureEkundayo TCThe World Academy of SciencesNational Research FoundationSouth African Medical Research Council3077https://www.ebi.ac.uk/biostudies/studies/S-EPMC6309461biostudies-literatureUnknown9One of the major challenges of modern medicine includes the failure of conventional protocols to characterize the pathogenicity of emerging pathogens. This is particularly apparent in the case of <i>Plesiomonas shigelloides</i>. Although a number of infections have been linked to this microorganism, experimental evidence of its virulence factors (VFs), obtained by traditional approaches, is somewhat inconclusive. Hence, it remains unclear whether <i>P. shigelloides</i> is a true or opportunistic one. In the current study, four publicly available whole-genome sequences of <i>P. shigelloides</i> (GN7, NCTC10360, 302-73, and LS1) were profiled using bioinformatics platforms to determine the putative candidate VFs to characterize the bacterial pathogenicity. Overall, 134 unique open reading frFrontiers in microbiologyPathogenomics of Virulence Traits of <i>Plesiomonas shigelloides</i> That Were Deemed Inconclusive by Traditional Experimental Approaches.PMC6309461Grant number:99796Ekundayo TCOkoh AIfalsePathogenomics of Virulence Traits of <i>Plesiomonas shigelloides</i> That Were Deemed Inconclusive by Traditional Experimental Approaches.One of the major challenges of modern medicine includes the failure of conventional protocols to characterize the pathogenicity of emerging pathogens. This is particularly apparent in the case of <i>Plesiomonas shigelloides</i>. Although a number of infections have been linked to this microorganism, experimental evidence of its virulence factors (VFs), obtained by traditional approaches, is somewhat inconclusive. Hence, it remains unclear whether <i>P. shigelloides</i> is a true or opportunistic one. In the current study, four publicly available whole-genome sequences of <i>P. shigelloides</i> (GN7, NCTC10360, 302-73, and LS1) were profiled using bioinformatics platforms to determine the putative candidate VFs to characterize the bacterial pathogenicity. Overall, 134 unique open reading fr2018-01-01T00:00:00Z20182026-05-06T05:28:13.498Z2019-03-26T22:36:44ZS-EPMC63094613062711910.3389/fmicb.2018.03077