biostudies-literaturePapachristou NEuropean Research CouncilHorizon 2020National Cancer InstituteNCI NIH HHSe0208808https://www.ebi.ac.uk/biostudies/studies/S-EPMC6312306biostudies-literatureUnknown13(12)Effective symptom management is a critical component of cancer treatment. Computational tools that predict the course and severity of these symptoms have the potential to assist oncology clinicians to personalize the patient's treatment regimen more efficiently and provide more aggressive and timely interventions. Three common and inter-related symptoms in cancer patients are depression, anxiety, and sleep disturbance. In this paper, we elaborate on the efficiency of Support Vector Regression (SVR) and Non-linear Canonical Correlation Analysis by Neural Networks (n-CCA) to predict the severity of the aforementioned symptoms between two different time points during a cycle of chemotherapy (CTX). Our results demonstrate that these two methods produced equivalent results for all three symptomPloS oneLearning from data to predict future symptoms of oncology patients.PMC6312306732679602289CA134900R01 CA134900Barnaghi PMaguire RMcCann LPapachristou NKatsaragakis SFox PAFurlong EPPuschmann DHu XApostolidis KLevine JDPaul SMReam EPatiraki EConley YPHammer MMiaskowski CCooper BKober KMWright FfalseLearning from data to predict future symptoms of oncology patients.Effective symptom management is a critical component of cancer treatment. Computational tools that predict the course and severity of these symptoms have the potential to assist oncology clinicians to personalize the patient's treatment regimen more efficiently and provide more aggressive and timely interventions. Three common and inter-related symptoms in cancer patients are depression, anxiety, and sleep disturbance. In this paper, we elaborate on the efficiency of Support Vector Regression (SVR) and Non-linear Canonical Correlation Analysis by Neural Networks (n-CCA) to predict the severity of the aforementioned symptoms between two different time points during a cycle of chemotherapy (CTX). Our results demonstrate that these two methods produced equivalent results for all three symptom2018-01-01T00:00:00Z20182026-07-09T12:09:23.919Z2019-03-26T22:35:57ZS-EPMC63123063059665810.1371/journal.pone.0208808