biostudies-literatureTsui INEI NIH HHSNICHD NIH HHSNIAID NIH HHSe20181104https://www.ebi.ac.uk/biostudies/studies/S-EPMC6317824biostudies-literatureUnknown142(4): media-1vid110.1542/5804915134001PEDS-VA_2018-1104<b>Video Abstract</b> OBJECTIVES: To characterize ophthalmic manifestations of confirmed or suspected antenatal Zika virus (ZIKV) exposure.<h4>Methods</h4>Infants with antenatal ZIKV exposure were referred for evaluation during the 2015-2016 Rio de Janeiro outbreak. Mothers with symptomatic ZIKV infection during pregnancy and/or infants with microcephaly or other findings that were suggestive of suspected antenatal exposure were tested with reverse transcriptase polymerase chain reaction (RT-PCR). Complete eye examinations were performed by pediatric ophthalmologists between January 2016 and February 2017. The main outcome measure was eye abnormalities in RT-PCR-positive and suspected (ie, not tested or RT-PCR-negative) antenatal ZIKV casePediatricsEye Findings in Infants With Suspected or Confirmed Antenatal Zika Virus Exposure.PMC6317824R21 EY028318K12 HD000849R21 AI129534Vasconcelos ZHaefeli LNielsen-Saines KNeves LMArumugaswami VSilveira Filho JCBRossetto JDGaw SLBrasil PZin AAPone MVDSAdachi KGomes SCMoreira MELPereira JPBelfort RPone SMZin OATsui IfalseEye Findings in Infants With Suspected or Confirmed Antenatal Zika Virus Exposure.: media-1vid110.1542/5804915134001PEDS-VA_2018-1104<b>Video Abstract</b> OBJECTIVES: To characterize ophthalmic manifestations of confirmed or suspected antenatal Zika virus (ZIKV) exposure.<h4>Methods</h4>Infants with antenatal ZIKV exposure were referred for evaluation during the 2015-2016 Rio de Janeiro outbreak. Mothers with symptomatic ZIKV infection during pregnancy and/or infants with microcephaly or other findings that were suggestive of suspected antenatal exposure were tested with reverse transcriptase polymerase chain reaction (RT-PCR). Complete eye examinations were performed by pediatric ophthalmologists between January 2016 and February 2017. The main outcome measure was eye abnormalities in RT-PCR-positive and suspected (ie, not tested or RT-PCR-negative) antenatal ZIKV case2018-01-01T00:00:00Z2018 Oct2026-07-09T12:10:43.651Z2026-07-09T11:10:27.629ZS-EPMC63178243021384310.1542/peds.2018-1104