{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9"],"submitter":["Sanahuja I"],"pubmed_abstract":["Temperate fish are particularly sensitive to low temperatures, especially in the northern Mediterranean area, where the cold season decreases fish-farm production and affects fish health. Recent studies have suggested that the skin mucus participates in overall fish defense and welfare, and therefore propose it as a target for non-invasive studies of fish status. Here, we determine the mucus interactome of differentially expressed proteins in a temperate fish model, gilthead sea bream (<i>Sparus aurata</i>), after chronic exposure to low temperatures (7 weeks at 14°C). The differentially expressed proteins were obtained by 2D-PAGE of mucus soluble proteins and further assessed by STRING analyses of the functional interactome based on protein-protein interactions. Complementarily, we determ"],"journal":["Frontiers in physiology"],"pagination":["1916"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6336924"],"repository":["biostudies-literature"],"pubmed_title":["Chronic Cold Stress Alters the Skin Mucus Interactome in a Temperate Fish Model."],"pmcid":["PMC6336924"],"pubmed_authors":["Sanchez-Nuno S","Fernandez-Alacid L","Sanahuja I","Ordonez-Grande B","Ibarz A"],"additional_accession":[]},"is_claimable":false,"name":"Chronic Cold Stress Alters the Skin Mucus Interactome in a Temperate Fish Model.","description":"Temperate fish are particularly sensitive to low temperatures, especially in the northern Mediterranean area, where the cold season decreases fish-farm production and affects fish health. Recent studies have suggested that the skin mucus participates in overall fish defense and welfare, and therefore propose it as a target for non-invasive studies of fish status. Here, we determine the mucus interactome of differentially expressed proteins in a temperate fish model, gilthead sea bream (<i>Sparus aurata</i>), after chronic exposure to low temperatures (7 weeks at 14°C). The differentially expressed proteins were obtained by 2D-PAGE of mucus soluble proteins and further assessed by STRING analyses of the functional interactome based on protein-protein interactions. Complementarily, we determ","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018","modification":"2026-04-08T01:54:29.522Z","creation":"2019-03-26T22:43:42Z"},"accession":"S-EPMC6336924","cross_references":{"pubmed":["30687126"],"doi":["10.3389/fphys.2018.01916"]}}