{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(1)"],"submitter":["Xie R"],"funding":["Special Research Fund for Traditional Chinese Medicine Science and Technology of Guangdong Provincial Hospital of Chinese Medicine"],"pubmed_abstract":["<h4>Introduction</h4>Tension-type headache (TTH) is the most prevalent neurological disease, with an estimated 1.5 billion cases worldwide. Pharmacotherapy should be considered by patients with TTH who have a limited response to non-pharmacological treatment. However, recommendations for the vast array of therapeutic drugs for TTH partially overlap, with conflicting recommendations for strength in different guidelines; these may confuse the decision-making process of clinicians. Hence, the aims of this study are to analyse the available direct and indirect evidence on different drug monotherapies for TTH in adults, and to generate a treatment ranking according to their efficacy and safety outcomes by using a Bayesian network meta-analysis (NMA).<h4>Methods and analysis</h4>We will systemat"],"journal":["BMJ open"],"pagination":["e023748"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6340443"],"repository":["biostudies-literature"],"pubmed_title":["Efficacy and safety of different drug monotherapies for tension-type headache in adults: study protocol for a Bayesian network meta-analysis."],"pmcid":["PMC6340443"],"pubmed_authors":["Tian J","Li H","Cai Y","Wang Y","Xie R"],"additional_accession":[]},"is_claimable":false,"name":"Efficacy and safety of different drug monotherapies for tension-type headache in adults: study protocol for a Bayesian network meta-analysis.","description":"<h4>Introduction</h4>Tension-type headache (TTH) is the most prevalent neurological disease, with an estimated 1.5 billion cases worldwide. Pharmacotherapy should be considered by patients with TTH who have a limited response to non-pharmacological treatment. However, recommendations for the vast array of therapeutic drugs for TTH partially overlap, with conflicting recommendations for strength in different guidelines; these may confuse the decision-making process of clinicians. Hence, the aims of this study are to analyse the available direct and indirect evidence on different drug monotherapies for TTH in adults, and to generate a treatment ranking according to their efficacy and safety outcomes by using a Bayesian network meta-analysis (NMA).<h4>Methods and analysis</h4>We will systemat","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Jan","modification":"2025-04-26T15:39:09.266Z","creation":"2019-03-26T22:47:38Z"},"accession":"S-EPMC6340443","cross_references":{"pubmed":["30647037"],"doi":["10.1136/bmjopen-2018-023748"]}}