{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Williams EC"],"funding":["VA Health Services Research & Development","National Institute on Alcohol Abuse and Alcoholism","NIAAA NIH HHS","HSRD VA","VA Health Services Research &amp; Development","COMpAAAS/Veterans Aging Cohort Study"],"pagination":["140-151"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6344313"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["23(1)"],"pubmed_abstract":["We evaluated associations between levels of alcohol use and HIV care continuum components using national Veterans Aging Cohort Study data for all patients with HIV and AUDIT-C screening (2/1/2008-9/30/2014). Poisson regression models evaluated associations between alcohol use levels (non-drinking, low-, medium-, high-, and very high-level drinking) and: (1) engagement with care (documented CD4 cells/µl or viral load copies/ml labs), (2) ART treatment (≥ 1 prescription), and (3) viral suppression (HIV RNA < 500 copies/ml) within one year. Among 33,224 patients, alcohol use level was inversely associated with all care continuum outcomes (all p < 0.001). Adjusted prevalence of care engagement ranged from 77.8% (95% CI 77.1-78.4%) for non-drinking to 69.1% (66.6-71.6%) for high-level drinking. The corresponding range for ART treatment was 74.0% (73.3-74.7%) to 60.1% (57.3-62.9%) and for viral suppression was 57.3% (56.5-58.1%) to 38.3% (35.6-41.1%). Greater alcohol use is associated with suboptimal HIV treatment across the HIV care continuum."],"journal":["AIDS and behavior"],"pubmed_title":["Level of Alcohol Use Associated with HIV Care Continuum Targets in a National U.S. Sample of Persons Living with HIV Receiving Healthcare."],"pmcid":["PMC6344313"],"funding_grant_id":["U24-AA020794","U01-AA020790","U10 AA013566","R21 AA022866","U01-AA020795","CDA 12-276","U01 AA020799","K24 AA022128","U24 AA020794","K24-AA022128","IK2 HX001161","U01 AA020790","U01 AA020795","U01-AA020799","R21AA022866-01"],"pubmed_authors":["Satre DD","Rubinsky AD","Gordon AJ","Bryant KJ","Lapham GT","Justice AC","Williams EC","McGinnis KA","Bradley KA","Richards JE","Marshall BDL","Fiellin DA","Catz SL","Edelman EJ","Matson TE"],"additional_accession":[]},"is_claimable":false,"name":"Level of Alcohol Use Associated with HIV Care Continuum Targets in a National U.S. Sample of Persons Living with HIV Receiving Healthcare.","description":"We evaluated associations between levels of alcohol use and HIV care continuum components using national Veterans Aging Cohort Study data for all patients with HIV and AUDIT-C screening (2/1/2008-9/30/2014). Poisson regression models evaluated associations between alcohol use levels (non-drinking, low-, medium-, high-, and very high-level drinking) and: (1) engagement with care (documented CD4 cells/µl or viral load copies/ml labs), (2) ART treatment (≥ 1 prescription), and (3) viral suppression (HIV RNA < 500 copies/ml) within one year. Among 33,224 patients, alcohol use level was inversely associated with all care continuum outcomes (all p < 0.001). Adjusted prevalence of care engagement ranged from 77.8% (95% CI 77.1-78.4%) for non-drinking to 69.1% (66.6-71.6%) for high-level drinking. The corresponding range for ART treatment was 74.0% (73.3-74.7%) to 60.1% (57.3-62.9%) and for viral suppression was 57.3% (56.5-58.1%) to 38.3% (35.6-41.1%). Greater alcohol use is associated with suboptimal HIV treatment across the HIV care continuum.","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Jan","modification":"2024-11-09T14:40:58.661Z","creation":"2020-05-22T01:12:57Z"},"accession":"S-EPMC6344313","cross_references":{"pubmed":["29995206"],"doi":["10.1007/s10461-018-2210-6"]}}