{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Nguyen VT"],"funding":["Dutch Research Council (NWO)","The Netherlands Organisation for Health Research and Development","COMPARE-H2020","European Commission","Wellcome Trust"],"pagination":["561-570"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6376849"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["74(3)"],"pubmed_abstract":["<h4>Objectives</h4>To investigate the risk of colonization with ESBL-producing Escherichia coli (ESBL-Ec) in humans in Vietnam associated with non-intensive chicken farming.<h4>Methods</h4>Faecal samples from 204 randomly selected farmers and their chickens, and from 306 age- and sex-matched community-based individuals who did not raise poultry were collected. Antimicrobial usage in chickens and humans was assessed by medicine cabinet surveys. WGS was employed to obtain a high-resolution genomic comparison between ESBL-Ec isolated from humans and chickens.<h4>Results</h4>The adjusted prevalence of ESBL-Ec colonization was 20.0% (95% CI 10.8%-29.1%) and 35.2% (95% CI 30.4%-40.1%) in chicken farms and humans in Vietnam, respectively. Colonization with ESBL-Ec in humans was associated with an"],"journal":["The Journal of antimicrobial chemotherapy"],"pubmed_title":["Limited contribution of non-intensive chicken farming to ESBL-producing Escherichia coli colonization in humans in Vietnam: an epidemiological and genomic analysis."],"pmcid":["PMC6376849"],"funding_grant_id":["106680/B/14/Z","643476","098051","110085/Z/15/Z","205100012"],"pubmed_authors":["Nguyen VT","Carrique-Mas JJ","Thai QH","Wagenaar JA","Parkhill J","Schultsz C","Thwaites G","Nguyen TNM","Ngo TH","Ho HM","Jamrozy D","Matamoros S"],"additional_accession":[]},"is_claimable":false,"name":"Limited contribution of non-intensive chicken farming to ESBL-producing Escherichia coli colonization in humans in Vietnam: an epidemiological and genomic analysis.","description":"<h4>Objectives</h4>To investigate the risk of colonization with ESBL-producing Escherichia coli (ESBL-Ec) in humans in Vietnam associated with non-intensive chicken farming.<h4>Methods</h4>Faecal samples from 204 randomly selected farmers and their chickens, and from 306 age- and sex-matched community-based individuals who did not raise poultry were collected. Antimicrobial usage in chickens and humans was assessed by medicine cabinet surveys. WGS was employed to obtain a high-resolution genomic comparison between ESBL-Ec isolated from humans and chickens.<h4>Results</h4>The adjusted prevalence of ESBL-Ec colonization was 20.0% (95% CI 10.8%-29.1%) and 35.2% (95% CI 30.4%-40.1%) in chicken farms and humans in Vietnam, respectively. Colonization with ESBL-Ec in humans was associated with an","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Mar","modification":"2025-04-25T23:19:57.517Z","creation":"2019-08-04T07:32:15Z"},"accession":"S-EPMC6376849","cross_references":{"pubmed":["30629197"],"doi":["10.1093/jac/dky506"]}}