biostudies-literatureUnknown14Serrao S<h4>Purpose</h4>To describe a case of endothelial damage after photorefractive keratectomy (PRK) combined with corneal cross-linking (CXL).<h4>Observations</h4>A 34-year-old man with diagnosis of stable keratoconus presented at our clinic complaining of vision loss in the left eye after same-day simultaneous PRK and CXL. One year postoperatively, slit-lamp examination showed central corneal haze and specular microscopy demonstrated reduced endothelial cell density compared with the preoperative state. Corrected distance visual acuity decreased from 18/20 preoperatively to 20/60 postoperatively. The thinnest corneal thickness value decreased from 432 μm preoperatively to 328 μm postoperatively.<h4>Conclusions and importance</h4>The present case demonstrates the importance of appropriate detAmerican journal of ophthalmology case reports32-34https://www.ebi.ac.uk/biostudies/studies/S-EPMC6378891biostudies-literatureCorneal endothelial damage after simultaneous PRK and corneal cross-linking in stable keratoconus.PMC6378891Serrao SLombardo MfalseCorneal endothelial damage after simultaneous PRK and corneal cross-linking in stable keratoconus.<h4>Purpose</h4>To describe a case of endothelial damage after photorefractive keratectomy (PRK) combined with corneal cross-linking (CXL).<h4>Observations</h4>A 34-year-old man with diagnosis of stable keratoconus presented at our clinic complaining of vision loss in the left eye after same-day simultaneous PRK and CXL. One year postoperatively, slit-lamp examination showed central corneal haze and specular microscopy demonstrated reduced endothelial cell density compared with the preoperative state. Corrected distance visual acuity decreased from 18/20 preoperatively to 20/60 postoperatively. The thinnest corneal thickness value decreased from 432 μm preoperatively to 328 μm postoperatively.<h4>Conclusions and importance</h4>The present case demonstrates the importance of appropriate det2019-01-01T00:00:00Z2019 Jun2025-04-26T09:00:54.509Z2019-06-06T23:23:57ZS-EPMC63788913081562110.1016/j.ajoc.2019.02.002