{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8"],"submitter":["Joshi C"],"pubmed_abstract":["<b>Background:</b><i>Punica granatum</i> extracts have been prescribed in traditional medicine for management of a variety of disease conditions including microbial infections. Generation of scientific evidence for validation of <i>P. granatum</i> peel extract's anti-pathogenic efficacy is required. <b>Methods:</b> Hydroalcoholic extract of <i>P. granatum</i> peel (PGPE), prepared by microwave assisted extraction method was evaluated for its quorum-modulatory potential against two different human-pathogenic bacteria viz. <i>Chromobacterium violaceum</i> and <i>Pseudomonas aeruginosa</i>. <b>Results:</b> This extract was able to modulate <i>in vitro</i> production of quorum sensing-regulated pigments in both these test bacteria at ≥5 μg/ml. Virulence traits of <i>P. aeruginosa</i> like haem"],"journal":["F1000Research"],"pagination":["70"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6392158"],"repository":["biostudies-literature"],"pubmed_title":["Anti-infective potential of hydroalcoholic extract of <i>Punica</i>  <i>granatum</i> peel against gram-negative bacterial pathogens."],"pmcid":["PMC6392158"],"pubmed_authors":["Patel P","Kothari V","Joshi C"],"additional_accession":[]},"is_claimable":false,"name":"Anti-infective potential of hydroalcoholic extract of <i>Punica</i>  <i>granatum</i> peel against gram-negative bacterial pathogens.","description":"<b>Background:</b><i>Punica granatum</i> extracts have been prescribed in traditional medicine for management of a variety of disease conditions including microbial infections. Generation of scientific evidence for validation of <i>P. granatum</i> peel extract's anti-pathogenic efficacy is required. <b>Methods:</b> Hydroalcoholic extract of <i>P. granatum</i> peel (PGPE), prepared by microwave assisted extraction method was evaluated for its quorum-modulatory potential against two different human-pathogenic bacteria viz. <i>Chromobacterium violaceum</i> and <i>Pseudomonas aeruginosa</i>. <b>Results:</b> This extract was able to modulate <i>in vitro</i> production of quorum sensing-regulated pigments in both these test bacteria at ≥5 μg/ml. Virulence traits of <i>P. aeruginosa</i> like haem","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019","modification":"2025-04-05T12:45:04.785Z","creation":"2019-06-06T22:46:01Z"},"accession":"S-EPMC6392158","cross_references":{"pubmed":["30828441"],"doi":["10.12688/f1000research.17430.2"]}}