{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bruun S"],"funding":["Innovationsfonden","The Netherlands Heart Foundation"],"pagination":["E235"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6412384"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(2)"],"pubmed_abstract":["Blood pressure (BP) and blood lipid profile (BLP) have been shown to track from childhood into adulthood, and n-3 long-chain polyunsaturated fatty acids (LC-PUFAs) in breast milk have been suggested as mediators of the beneficial long-term effect of breastfeeding on BP and BLP. We aimed to investigate associations between n-3 LC-PUFA content in breast milk at 4 months postpartum and offspring BP and BLP in early life. BP and BLP were measured at 4, 18, and 36 months. Statistical analyses were sex-stratified and adjusted for gestational age, maternal pre-pregnancy body mass index (BMI), and maternal educational level. Based on 336 mother-child dyads, high n-3 LC-PUFA in breast milk was inversely associated with systolic and diastolic BP in boys at 4 months (β = -20.0 (95% CI = -33.4, -6.7),"],"journal":["Nutrients"],"pubmed_title":["Content of n-3 LC-PUFA in Breast Milk Four Months Postpartum is Associated with Infancy Blood Pressure in Boys and Infancy Blood Lipid Profile in Girls."],"pmcid":["PMC6412384"],"funding_grant_id":["T2013025","5016-00075B"],"pubmed_authors":["Boysen Sandberg M","Stark KD","van Rossem L","Zachariassen G","Michaelsen KF","Sorensen J","Bruun S","Husby S","Lauritzen L","Neergaard Jacobsen L"],"additional_accession":[]},"is_claimable":false,"name":"Content of n-3 LC-PUFA in Breast Milk Four Months Postpartum is Associated with Infancy Blood Pressure in Boys and Infancy Blood Lipid Profile in Girls.","description":"Blood pressure (BP) and blood lipid profile (BLP) have been shown to track from childhood into adulthood, and n-3 long-chain polyunsaturated fatty acids (LC-PUFAs) in breast milk have been suggested as mediators of the beneficial long-term effect of breastfeeding on BP and BLP. We aimed to investigate associations between n-3 LC-PUFA content in breast milk at 4 months postpartum and offspring BP and BLP in early life. BP and BLP were measured at 4, 18, and 36 months. Statistical analyses were sex-stratified and adjusted for gestational age, maternal pre-pregnancy body mass index (BMI), and maternal educational level. Based on 336 mother-child dyads, high n-3 LC-PUFA in breast milk was inversely associated with systolic and diastolic BP in boys at 4 months (β = -20.0 (95% CI = -33.4, -6.7),","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Jan","modification":"2026-07-17T00:10:57.876Z","creation":"2019-08-04T07:41:04Z"},"accession":"S-EPMC6412384","cross_references":{"pubmed":["30678226"],"doi":["10.3390/nu11020235"]}}