biostudies-literatureLi DNatural Science Foundation of Hubei ProvinceNational Natural Science Foundation of China2791-2795https://www.ebi.ac.uk/biostudies/studies/S-EPMC6419947biostudies-literatureUnknown10(9)Electrochemical oxidative C-H/S-H cross-coupling has been developed to construct the C-S bond in a highly straightforward and efficient manner. Various enamines and (hetero)aryl thiols could be transformed smoothly under undivided electrolytic cell conditions. Moreover, this electrosynthesis strategy not only avoided the use of chemical oxidants and transition metal catalysts, but also exhibited excellent atom economy.Chemical scienceElectrochemical oxidative C-H/S-H cross-coupling between enamines and thiophenols with H₂ evolution.PMC641994721390402, 215201020032017CFA010Lu LWang PLi SLi DWang SPeng CCong HChen YHLei AfalseElectrochemical oxidative C-H/S-H cross-coupling between enamines and thiophenols with H₂ evolution.Electrochemical oxidative C-H/S-H cross-coupling has been developed to construct the C-S bond in a highly straightforward and efficient manner. Various enamines and (hetero)aryl thiols could be transformed smoothly under undivided electrolytic cell conditions. Moreover, this electrosynthesis strategy not only avoided the use of chemical oxidants and transition metal catalysts, but also exhibited excellent atom economy.2019-01-01T00:00:00Z2019 Mar2026-05-07T10:31:16.227Z2025-06-01T01:17:45.562ZS-EPMC64199473099699910.1039/c8sc05143g