biostudies-literatureYang SNatural Sciences and Engineering Research Council of Canada101https://www.ebi.ac.uk/biostudies/studies/S-EPMC6420592biostudies-literatureUnknown14(1)A suitable surface is vital for maintaining or even promoting cells' function and communication. Recently, studies show that nanostructured coatings could have a potential in improving cell adhesion. However, it hardly minimizes the contamination by using traditional solution-coating technology. Matrix-assisted pulsed laser evaporation (MAPLE) technique is a contamination-free process and demonstrates an efficient process to deposit biopolymer without damaging their backbone on the surface of various substrates. Here, upconversion nanoparticles (NaGdF4: Yb3+, Er3+) with/without immunoglobulin G (IgG) modification were produced by a one-pot synthesis method. The average size of the upconversion nanoparticles (UCNPs) is 50 ± 8 nm. IgG bio-conjugated on the surface of UCNPs can be directly obNanoscale research lettersDeposition of Antibody Modified Upconversion Nanoparticles on Glass by a Laser-Assisted Method to Improve the Performance of Cell Culture.PMC6420592R4036A25Tse WHZhang JYang SfalseDeposition of Antibody Modified Upconversion Nanoparticles on Glass by a Laser-Assisted Method to Improve the Performance of Cell Culture.A suitable surface is vital for maintaining or even promoting cells' function and communication. Recently, studies show that nanostructured coatings could have a potential in improving cell adhesion. However, it hardly minimizes the contamination by using traditional solution-coating technology. Matrix-assisted pulsed laser evaporation (MAPLE) technique is a contamination-free process and demonstrates an efficient process to deposit biopolymer without damaging their backbone on the surface of various substrates. Here, upconversion nanoparticles (NaGdF4: Yb3+, Er3+) with/without immunoglobulin G (IgG) modification were produced by a one-pot synthesis method. The average size of the upconversion nanoparticles (UCNPs) is 50 ± 8 nm. IgG bio-conjugated on the surface of UCNPs can be directly ob2019-01-01T00:00:00Z2019 Mar2025-06-01T01:19:06.188Z2025-06-01T01:19:06.188ZS-EPMC64205923087739910.1186/s11671-019-2918-x