{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Mahalingaiah S"],"funding":["NIEHS NIH HHS","NCI NIH HHS"],"pagination":["512-519"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6459285"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["33(3)"],"pubmed_abstract":["<h4>Study question</h4>What is the association between perimenarchal exposure to total suspended particulate (TSP) in air, menstrual irregularity phenotypes and time to menstrual cycle regularity?<h4>Summary answer</h4>Exposures to TSP during high school are associated with slightly increased odds of menstrual irregularity and longer time to regularity in high school and early adulthood.<h4>What is known already</h4>The menstrual cycle is responsive to hormonal regulation. Particulate matter air pollution has demonstrated hormonal activity. However, it is not known if air pollution is associated with menstrual cycle regularity.<h4>Study design, size, duration</h4>Cross sectional study of 34 832 of the original 116 430 women (29.91%) enrolled in 1989 from the Nurses' Health Study II (NHSII)"],"journal":["Human reproduction (Oxford, England)"],"pubmed_title":["Perimenarchal air pollution exposure and menstrual disorders."],"pmcid":["PMC6459285"],"funding_grant_id":["R01 CA050385","UM1 CA176726","R01 ES017017"],"pubmed_authors":["Hart JE","Missmer SE","Cheng JJ","Chavarro J","Mahalingaiah S","Laden F"],"additional_accession":[]},"is_claimable":false,"name":"Perimenarchal air pollution exposure and menstrual disorders.","description":"<h4>Study question</h4>What is the association between perimenarchal exposure to total suspended particulate (TSP) in air, menstrual irregularity phenotypes and time to menstrual cycle regularity?<h4>Summary answer</h4>Exposures to TSP during high school are associated with slightly increased odds of menstrual irregularity and longer time to regularity in high school and early adulthood.<h4>What is known already</h4>The menstrual cycle is responsive to hormonal regulation. Particulate matter air pollution has demonstrated hormonal activity. However, it is not known if air pollution is associated with menstrual cycle regularity.<h4>Study design, size, duration</h4>Cross sectional study of 34 832 of the original 116 430 women (29.91%) enrolled in 1989 from the Nurses' Health Study II (NHSII)","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Mar","modification":"2026-07-17T01:33:39.622Z","creation":"2019-06-06T21:10:10Z"},"accession":"S-EPMC6459285","cross_references":{"pubmed":["29377993"],"doi":["10.1093/humrep/dey005"]}}