{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Mollan SP"],"funding":["DH | NIHR | Research Trainees Coordinating Centre","Medical Research Council","National Institute for Health Research (NIHR)"],"pagination":["478-485"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6460708"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["33(3)"],"pubmed_abstract":["<h4>Objective</h4>To quantify the hospital burden and health economic impact of idiopathic intracranial hypertension.<h4>Methods</h4>Hospital Episode Statistics (HES) national data was extracted between 1st January 2002 and 31st December 2016. All those within England with a diagnosis of idiopathic intracranial hypertension were included. Those with secondary causes of raised intracranial pressure such as tumours, hydrocephalus and cerebral venous sinus thrombosis were excluded.<h4>Results</h4>A total of 23,182 new IIH cases were diagnosed. Fifty-two percent resided in the most socially deprived areas (quintiles 1 and 2). Incidence rose between 2002 and 2016 from 2.3 to 4.7 per 100,000 in the general population. Peak incidence occurred in females aged 25 (15.2 per 100,000). 91.6% were treated medically, 7.6% had a cerebrospinal fluid diversion procedure, 0.7% underwent bariatric surgery and 0.1% had optic nerve sheath fenestration. Elective caesarean sections rates were significantly higher in IIH (16%) compared to the general population (9%), p < 0.005. Admission rates rose by 442% between 2002 and 2014, with 38% having repeated admissions in the year following diagnosis. Duration of hospital admission was 2.7 days (8.8 days for those having CSF diversion procedures). Costs rose from £9.2 to £50 million per annum over the study period with costs forecasts of £462 million per annum by 2030.<h4>Conclusions</h4>IIH incidence is rising (by greater than 100% over the study), highest in areas of social deprivation and mirroring obesity trends. Re-admissions rates are high and growing yearly. The escalating population and financial burden of IIH has wide reaching implications for the health care system."],"journal":["Eye (London, England)"],"pubmed_title":["The expanding burden of idiopathic intracranial hypertension."],"pmcid":["PMC6460708"],"funding_grant_id":["MR/K015184/1","NIHR-CS-011-028"],"pubmed_authors":["Aguiar M","Mollan SP","Sinclair AJ","Evison F","Frew E"],"additional_accession":[]},"is_claimable":false,"name":"The expanding burden of idiopathic intracranial hypertension.","description":"<h4>Objective</h4>To quantify the hospital burden and health economic impact of idiopathic intracranial hypertension.<h4>Methods</h4>Hospital Episode Statistics (HES) national data was extracted between 1st January 2002 and 31st December 2016. All those within England with a diagnosis of idiopathic intracranial hypertension were included. Those with secondary causes of raised intracranial pressure such as tumours, hydrocephalus and cerebral venous sinus thrombosis were excluded.<h4>Results</h4>A total of 23,182 new IIH cases were diagnosed. Fifty-two percent resided in the most socially deprived areas (quintiles 1 and 2). Incidence rose between 2002 and 2016 from 2.3 to 4.7 per 100,000 in the general population. Peak incidence occurred in females aged 25 (15.2 per 100,000). 91.6% were treated medically, 7.6% had a cerebrospinal fluid diversion procedure, 0.7% underwent bariatric surgery and 0.1% had optic nerve sheath fenestration. Elective caesarean sections rates were significantly higher in IIH (16%) compared to the general population (9%), p < 0.005. Admission rates rose by 442% between 2002 and 2014, with 38% having repeated admissions in the year following diagnosis. Duration of hospital admission was 2.7 days (8.8 days for those having CSF diversion procedures). Costs rose from £9.2 to £50 million per annum over the study period with costs forecasts of £462 million per annum by 2030.<h4>Conclusions</h4>IIH incidence is rising (by greater than 100% over the study), highest in areas of social deprivation and mirroring obesity trends. Re-admissions rates are high and growing yearly. The escalating population and financial burden of IIH has wide reaching implications for the health care system.","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Mar","modification":"2024-02-15T22:37:15.512Z","creation":"2019-07-25T07:13:51Z"},"accession":"S-EPMC6460708","cross_references":{"pubmed":["30356129"],"doi":["10.1038/s41433-018-0238-5"]}}