{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kunath BJ"],"funding":["Norges Forskningsråd","European Research Council"],"pagination":["603-617"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6461833"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(3)"],"pubmed_abstract":["Microbial communities that degrade lignocellulosic biomass are typified by high levels of species- and strain-level complexity, as well as synergistic interactions between both cellulolytic and non-cellulolytic microorganisms. Coprothermobacter proteolyticus frequently dominates thermophilic, lignocellulose-degrading communities with wide geographical distribution, which is in contrast to reports that it ferments proteinaceous substrates and is incapable of polysaccharide hydrolysis. Here we deconvolute a highly efficient cellulose-degrading consortium (SEM1b) that is co-dominated by Clostridium (Ruminiclostridium) thermocellum and multiple heterogenic strains affiliated to C. proteolyticus. Metagenomic analysis of SEM1b recovered metagenome-assembled genomes (MAGs) for each constituent po"],"journal":["The ISME journal"],"pubmed_title":["From proteins to polysaccharides: lifestyle and genetic evolution of Coprothermobacter proteolyticus."],"pmcid":["PMC6461833"],"funding_grant_id":["336355","250479","221568"],"pubmed_authors":["Arntzen MO","Delogu F","Eijsink VGH","Naas AE","Henrissat B","Pope PB","Kunath BJ","Hvidsten TR"],"additional_accession":[]},"is_claimable":false,"name":"From proteins to polysaccharides: lifestyle and genetic evolution of Coprothermobacter proteolyticus.","description":"Microbial communities that degrade lignocellulosic biomass are typified by high levels of species- and strain-level complexity, as well as synergistic interactions between both cellulolytic and non-cellulolytic microorganisms. Coprothermobacter proteolyticus frequently dominates thermophilic, lignocellulose-degrading communities with wide geographical distribution, which is in contrast to reports that it ferments proteinaceous substrates and is incapable of polysaccharide hydrolysis. Here we deconvolute a highly efficient cellulose-degrading consortium (SEM1b) that is co-dominated by Clostridium (Ruminiclostridium) thermocellum and multiple heterogenic strains affiliated to C. proteolyticus. Metagenomic analysis of SEM1b recovered metagenome-assembled genomes (MAGs) for each constituent po","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Mar","modification":"2026-04-15T21:34:34.147Z","creation":"2019-10-11T07:01:30Z"},"accession":"S-EPMC6461833","cross_references":{"pubmed":["30315317"],"doi":["10.1038/s41396-018-0290-y"]}}