biostudies-literatureCraig MEGerman Federal Ministry for Education and ResearchLeona M. and Harry B. Helmsley Charitable TrustNIDDK NIH HHSRoyal College of Paediatrics and Child HealthJDRF AustraliaNational Health and Medical Research Council1034-1040https://www.ebi.ac.uk/biostudies/studies/S-EPMC6463736biostudies-literatureUnknown40(8)<h4>Objective</h4>Celiac disease (CD) has a recognized association with type 1 diabetes. We examined international differences in CD prevalence and clinical characteristics of youth with coexisting type 1 diabetes and CD versus type 1 diabetes only.<h4>Research design and methods</h4>Data sources were as follows: the Prospective Diabetes Follow-up Registry (DPV) (Germany/Austria); the T1D Exchange Clinic Network (T1DX) (U.S.); the National Paediatric Diabetes Audit (NPDA) (U.K. [England/Wales]); and the Australasian Diabetes Data Network (ADDN) (Australia). The analysis included 52,721 youths <18 years of age with a clinic visit between April 2013 and March 2014. Multivariable linear and logistic regression models were constructed to analyze the relationship between outcomes (HbA<sub>1c</sDiabetes carePrevalence of Celiac Disease in 52,721 Youth With Type 1 Diabetes: International Comparison Across Three Continents.PMC6463736APP1045777T32 DK06552217-2011-665Jeandron DMarkman EWollam BStarkman HMcGill JCorathers SMawhorter CCriego ADuBose SFudge BSchweiger MGandica RThornton HHarwood KSinnott RFisher LMeehan CSandstrom AYoung LHoll RWHoward NMinnock PLaffel LMiller CMonzavi RPotter AQuattrin TCaldas-Vasquez MWhite BKissel SBrendle FDeeb LTawa ODugdale DCBethin KDove AKhakpour DCusi KQuinn MKruger DKlein JMowry CRudolph JT1D Exchange Clinic Network (T1DX)Garnes EJoarder FHenson DSlover RGerard-Gonzalez ABeasley SDavis LKagan EVance CAyala NDavis EWalravens PSalamati SCraig MENelson BMurray MGregg BSpeer HWagner CSteffen ANathan BBulger JKennedy LAbel KLTansey MFrohlich-Reiterer EGreenbaum COlson BMcCrossin RMyers LBode BMartinez CWarnock TTamborlane WYulatic RBlashke CArnold KHassing JKuhns KNadeau KBergant SJonas ALipton MWeiss JSpruill AWoolfield NLess JSteck AGuevarra FSabanosh KTham ERacine MCohoon CMiyazaki BRuelas VDonaghue KBergenstal RPhillips RBrault JCintron MRosenfeld NPontifes MQuintana RHarris BSimmons JHDuclos MHashiguchi MWeinstock RAdi SCengiz EKaufman FDolan LRohrbacher KLibman IFox MGitelman SFox LConwell LKlingensmith GFailor RATricome JClifton MJStreet ATsalikian EProspective Diabetes Follow-up Registry (DPV) initiativeWarner JTSive APeterson CHofman PBaldwin DKohm KHefty DPeterson VClare-Salzler MKramer JCook SNational Paediatric Diabetes Audit (NPDA) and the Royal College of Paediatrics and Child HealthHamaty MAhmann AWhitson-Jones DThomas JBerlanga RJones TWSchroeder LMaahs DThomas LSchanuel JTello AEdelen RWolfsdorf JBlack MCheung CBuckingham BKittelsrud JWeiner LStandiford DIzquierdo RCox JWood JBzdick SWood MRigby SBobik CSilverman LZgorski MKing BRMatfin GHaller MRepas TJefferies CSulik MTridgell DDuke JLargay JCuffee JHallanger-Johnson JZoungas SRamey MForghani NHaines JFalk TSmart CDiaz ABergman PGilliam LSchmid KYi-Frazier JDerby TPeleckis AWard RGottschalk MClements MStone MHoops STasi CGubitosi-Klug RFlannery TBorgwardt TAli OSmith KPrudent AShah ACabbage JWoerner SCalikoglu AWilliams MZimmermann ACopeland KSheehan EWilliams JFrost CScoggin PPatel PTolbert JDuncan VSchatz DDalton-Bakes CKatz MLeschyshyn JHester LEbner-Lyon LCraig MChin DBrandenburg VCoughenour TGonzalez JRobison BSosenko JBoyle CTHathway JHartigan CBaugh HMarchiando RHubacz LCruz CBacha FCalvano TPihoker CCain CHurst SRecklein CGreenberg ERepaske DCohen MOrasko AWebb KPitukcheewanont PMassaro EGray LZeitler PPrinz NSheikh UFitch RBiersdorf DHolmes-Walker JBuechler LPeters AKonstantinopoulos PGupta ARickels MChaudhari MDaniel MMehta SKucheruk OHoffman RDiMeglio LEvans TMauras NWilli SKleis LTrence DWiltshire EJones JCampbell FMAmundson DHosey RCastle JJones TWisse BEnglert KCemeroglu AKogler ADamberg GBlehm JBills VSellers SIchihara BBurgh KRaymond JMarie MSTurpin AWysham CCady NMoran AHannon TChao LBellin MLiljenquist DLafferty ALipman TBedard JPena APostellon DKollipara SDeBoer MStoker AWales JClark LPollack SRoark AElrod ACaswell KWebber CHofer SEBatts EBeck JDeSantis ASimmons JKlinepeter SAleppo-Kacmarek GMadison HHanson DConroy CBogan CMcCulloch-Olson MHaymond MChase PSlater HClark SWagh SRohrs HLee MWadwa PLee JHalford JKim MAppiagyei-Dankah YRedondo MMcClave CRaman VPascoe MThomson PLock JPGassner HWheeler KRodda CDamaso LPitts ABlackman SCotterill ABanion CRaman SMatheson DSilverstein JGilson EGoland RPrice DTrinh LMichels APrasad VChettout NBrown HBarker JKichler JSolorzano CBBrown CColman PGarg SEcker MSeiple DLindmark KBerry TDaniels MHarlan DBurt CWasson MJack MHolman NTan MManseau KAdkins DBuse JKaminski BWillis SVerge CFairchild JKearns SFoster CKelsy MBatch JCoffey JFridlington AAmbler GOrr DCerame BHirsch IRewers MJanci MRodriguez HRewers AConboy PNaidu AHaro HTorok CMaahs DMPowers MBenjamin RTassopoulos ACampbell WDeGrote KReh CEason AZipf WRose DKing BAustralasian Diabetes Data Network (ADDN)Nguyen COdegard PDigman CCappiello DCameron FReifeis EBrown TCouper JfalsePrevalence of Celiac Disease in 52,721 Youth With Type 1 Diabetes: International Comparison Across Three Continents.<h4>Objective</h4>Celiac disease (CD) has a recognized association with type 1 diabetes. We examined international differences in CD prevalence and clinical characteristics of youth with coexisting type 1 diabetes and CD versus type 1 diabetes only.<h4>Research design and methods</h4>Data sources were as follows: the Prospective Diabetes Follow-up Registry (DPV) (Germany/Austria); the T1D Exchange Clinic Network (T1DX) (U.S.); the National Paediatric Diabetes Audit (NPDA) (U.K. [England/Wales]); and the Australasian Diabetes Data Network (ADDN) (Australia). The analysis included 52,721 youths <18 years of age with a clinic visit between April 2013 and March 2014. Multivariable linear and logistic regression models were constructed to analyze the relationship between outcomes (HbA<sub>1c</s2017-01-01T00:00:00Z2017 Aug2026-07-17T01:39:21.405Z2019-06-06T22:55:49ZS-EPMC64637362854622210.2337/dc16-2508