biostudies-literatureUnknown19(1)Ibeneme SC<h4>Background</h4>Compromised immune function, associated with human immune deficiency virus(HIV) infection, is improved by antiretroviral therapy(ART) which also decreases bone mineral density(BMD), and possibly the quality of life(QoL). However, physical(aerobic/resistance) exercises, were reported to induce reverse effects in uninfected individuals and were appraised in the literature for evidence of similar benefits in people living with HIV/AIDS(PLWHA). The main study objective was to evaluate the impact of physical (aerobic and resistance) exercises on CD⁴⁺ count, BMD and QoL in PLWHA.<h4>Methods</h4>A systematic review was conducted using the Cochrane Collaboration protocol. Searching databases, up to June 2017, only randomized control trials investigating the effects ofBMC infectious diseases340https://www.ebi.ac.uk/biostudies/studies/S-EPMC6480814biostudies-literatureImpact of physical exercises on immune function, bone mineral density, and quality of life in people living with HIV/AIDS: a systematic review with meta-analysis.PMC6480814Ezeofor SNOkere PCIloanusi NIEzuma ADFortwengel GIrem FOIbeneme SCEzenwankwo FENnamani AODim NRfalseImpact of physical exercises on immune function, bone mineral density, and quality of life in people living with HIV/AIDS: a systematic review with meta-analysis.<h4>Background</h4>Compromised immune function, associated with human immune deficiency virus(HIV) infection, is improved by antiretroviral therapy(ART) which also decreases bone mineral density(BMD), and possibly the quality of life(QoL). However, physical(aerobic/resistance) exercises, were reported to induce reverse effects in uninfected individuals and were appraised in the literature for evidence of similar benefits in people living with HIV/AIDS(PLWHA). The main study objective was to evaluate the impact of physical (aerobic and resistance) exercises on CD⁴⁺ count, BMD and QoL in PLWHA.<h4>Methods</h4>A systematic review was conducted using the Cochrane Collaboration protocol. Searching databases, up to June 2017, only randomized control trials investigating the effects of2019-01-01T00:00:00Z2019 Apr2025-04-20T03:21:02.215Z2019-06-06T22:48:39ZS-EPMC64808143101426210.1186/s12879-019-3916-4