{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["41(3)"],"submitter":["Najjar RS"],"funding":["Johnsie and Aubary Montgomery Institute of Medical Education and Research"],"pubmed_abstract":["<h4>Background</h4>Cardiovascular disease (CVD) is a major economic burden in the United States. CVD risk factors, particularly hypertension and hypercholesterolemia, are typically treated with drug therapy. Five-year efficacy of such drugs to prevent CVD is estimated to be 5%. Plant-based diets have emerged as effective mitigators of these risk factors.<h4>Hypothesis</h4>The implementation of a defined, plant-based diet for 4 weeks in an outpatient clinical setting may mitigate CVD risk factors and reduce patient drug burden.<h4>Methods</h4>Participants consumed a plant-based diet consisting of foods prepared in a defined method in accordance with a food-classification system. Participants consumed raw fruits, vegetables, seeds, and avocado. All animal products were excluded from the diet"],"journal":["Clinical cardiology"],"pagination":["307-313"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6489725"],"repository":["biostudies-literature"],"pubmed_title":["A defined, plant-based diet utilized in an outpatient cardiovascular clinic effectively treats hypercholesterolemia and hypertension and reduces medications."],"pmcid":["PMC6489725"],"pubmed_authors":["Najjar RS","Montgomery BD","Moore CE"],"additional_accession":[]},"is_claimable":false,"name":"A defined, plant-based diet utilized in an outpatient cardiovascular clinic effectively treats hypercholesterolemia and hypertension and reduces medications.","description":"<h4>Background</h4>Cardiovascular disease (CVD) is a major economic burden in the United States. CVD risk factors, particularly hypertension and hypercholesterolemia, are typically treated with drug therapy. Five-year efficacy of such drugs to prevent CVD is estimated to be 5%. Plant-based diets have emerged as effective mitigators of these risk factors.<h4>Hypothesis</h4>The implementation of a defined, plant-based diet for 4 weeks in an outpatient clinical setting may mitigate CVD risk factors and reduce patient drug burden.<h4>Methods</h4>Participants consumed a plant-based diet consisting of foods prepared in a defined method in accordance with a food-classification system. Participants consumed raw fruits, vegetables, seeds, and avocado. All animal products were excluded from the diet","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Mar","modification":"2025-04-04T08:24:10.354Z","creation":"2019-09-04T07:03:23Z"},"accession":"S-EPMC6489725","cross_references":{"pubmed":["29575002"],"doi":["10.1002/clc.22863"]}}