{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Vicent-Gil M"],"funding":["Spanish Ministry of Science and Innovation, Instituto Carlos III"],"pagination":["135"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6501398"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["19(1)"],"pubmed_abstract":["<h4>Background</h4>Given the limitation of pharmacological treatments to treat cognitive symptoms in patients with Major Depressive Disorder (MDD), cognitive remediation programs has been proposed as a possible procognitive intervention but findings are not conclusive. This study investigates the efficacy of an INtegral Cognitive REMediation (INCREM) that includes a combination of a Functional Remediation (FR) strategy plus a Computerized Cognitive Training (CCT) in order to improve not only cognitive performance but also the psychosocial functioning and the quality of life.<h4>Methods</h4>A single blind randomized controlled clinical trial in 81 patients with a diagnosis of MDD in clinical remission or in partial remission. Participants will be randomized to one of three conditions: INCRE"],"journal":["BMC psychiatry"],"pubmed_title":["Testing the efficacy of INtegral Cognitive REMediation (INCREM) in major depressive disorder: study protocol for a randomized clinical trial."],"pmcid":["PMC6501398"],"funding_grant_id":["PI17/00056"],"pubmed_authors":["Gonzalez-Simarro S","Perez-Blanco J","Trujols J","Cardoner N","Raventos B","Bonnin CDM","de Diego-Adelino J","Portella MJ","Serra-Blasco M","Vicent-Gil M","Puigdemont D","Martinez-Aran A","Marin-Martinez ED"],"additional_accession":[]},"is_claimable":false,"name":"Testing the efficacy of INtegral Cognitive REMediation (INCREM) in major depressive disorder: study protocol for a randomized clinical trial.","description":"<h4>Background</h4>Given the limitation of pharmacological treatments to treat cognitive symptoms in patients with Major Depressive Disorder (MDD), cognitive remediation programs has been proposed as a possible procognitive intervention but findings are not conclusive. This study investigates the efficacy of an INtegral Cognitive REMediation (INCREM) that includes a combination of a Functional Remediation (FR) strategy plus a Computerized Cognitive Training (CCT) in order to improve not only cognitive performance but also the psychosocial functioning and the quality of life.<h4>Methods</h4>A single blind randomized controlled clinical trial in 81 patients with a diagnosis of MDD in clinical remission or in partial remission. Participants will be randomized to one of three conditions: INCRE","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 May","modification":"2025-05-31T22:19:53.527Z","creation":"2019-06-06T23:11:28Z"},"accession":"S-EPMC6501398","cross_references":{"pubmed":["31060604"],"doi":["10.1186/s12888-019-2117-4"]}}