{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Haller BC"],"funding":["National Institutes of Health","NIGMS NIH HHS"],"pagination":["1101-1109"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6501880"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["36(5)"],"pubmed_abstract":["The SLiM forward genetic simulation framework has proved to be a powerful and flexible tool for population genetic modeling. However, as a complex piece of software with many features that allow simulating a diverse assortment of evolutionary models, its initial learning curve can be difficult. Here we provide a step-by-step demonstration of how to build a simple evolutionary model in SLiM 3, to help new users get started. We will begin with a panmictic neutral model, and build up to a model of the evolution of a polygenic quantitative trait under selection for an environmental phenotypic optimum."],"journal":["Molecular biology and evolution"],"pubmed_title":["Evolutionary Modeling in SLiM 3 for Beginners."],"pmcid":["PMC6501880"],"funding_grant_id":["R01GM127418","R01 GM127418"],"pubmed_authors":["Haller BC","Messer PW"],"additional_accession":[]},"is_claimable":false,"name":"Evolutionary Modeling in SLiM 3 for Beginners.","description":"The SLiM forward genetic simulation framework has proved to be a powerful and flexible tool for population genetic modeling. However, as a complex piece of software with many features that allow simulating a diverse assortment of evolutionary models, its initial learning curve can be difficult. Here we provide a step-by-step demonstration of how to build a simple evolutionary model in SLiM 3, to help new users get started. We will begin with a panmictic neutral model, and build up to a model of the evolution of a polygenic quantitative trait under selection for an environmental phenotypic optimum.","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 May","modification":"2025-05-29T21:52:25.9Z","creation":"2025-05-29T21:52:25.9Z"},"accession":"S-EPMC6501880","cross_references":{"pubmed":["30590560"],"doi":["10.1093/molbev/msy237"]}}