biostudies-literatureJenkins SNUniversity of California’s Agriculture and Natural Resources competitiveUSDA National Institute of Food and Agriculturee6749https://www.ebi.ac.uk/biostudies/studies/S-EPMC6507897biostudies-literatureUnknown7<h4>Background</h4>Coagulase negative <i>Staphylococcus</i> (CNS) species are currently the most prevalent intra-mammary pathogens causing subclinical mastitis and occasional clinical mastitis or persistent infection in lactating dairy cattle. More than 10 CNS species have been identified, but they are generally managed as one group on most dairies in the United States. However, improved management decisions and treatment outcomes may be achieved with better understanding of the prevalent species, pathogenicity and strain diversity within and across dairies.<h4>Methodology</h4>A total of 604 CNS isolates were cultured from milk samples collected during a dry-cow treatment clinical trial conducted on 6 dairy herds in 4 states in the US. All the study cows were randomized to receive 1 of thePeerJMolecular epidemiology of coagulase-negative <i>Staphylococcus</i> species isolated at different lactation stages from dairy cattle in the United States.PMC650789715-3765CALV-AH-323 projectRapnicki PJenkins SNArruda AGTimms LLAly SSRossitto PVLehenbauer TWGodden SChampagne JGorden PJOkello EPenedo MCTfalseMolecular epidemiology of coagulase-negative <i>Staphylococcus</i> species isolated at different lactation stages from dairy cattle in the United States.<h4>Background</h4>Coagulase negative <i>Staphylococcus</i> (CNS) species are currently the most prevalent intra-mammary pathogens causing subclinical mastitis and occasional clinical mastitis or persistent infection in lactating dairy cattle. More than 10 CNS species have been identified, but they are generally managed as one group on most dairies in the United States. However, improved management decisions and treatment outcomes may be achieved with better understanding of the prevalent species, pathogenicity and strain diversity within and across dairies.<h4>Methodology</h4>A total of 604 CNS isolates were cultured from milk samples collected during a dry-cow treatment clinical trial conducted on 6 dairy herds in 4 states in the US. All the study cows were randomized to receive 1 of the2019-01-01T00:00:00Z20192025-04-22T00:11:08.057Z2019-06-06T23:29:11ZS-EPMC65078973111906810.7717/peerj.6749