biostudies-literatureUnknown7Matranga D<h4>Objective</h4>The aim of this study was to introduce the VaccinaTion & Hpv Knowledge (THinK) questionnaire to assess knowledge about human papillomavirus (HPV) and attitude to HPV-vaccination. Its reliability and validity was demonstrated in a sample of women living in Sicily (southern Italy).<h4>Methods</h4>A cross-sectional survey was conducted on a sample of 220 women at the "Paolo Giaccone" University Hospital in Palermo (Sicily), aged 18-61. Data were analyzed through Cronbach's alpha and exploratory factor analysis, followed by a structural equation model with measurement component. The two-level data structure was explicitly considered.<h4>Results</h4>Three dimensions were found: "knowledge of HPV infection (kHPV), "Attitude to be vaccinated against HPV (aHPV)" and "Knowledge abPeerJe6254https://www.ebi.ac.uk/biostudies/studies/S-EPMC6511389biostudies-literatureThe vaccina<i>T</i>ion & <i>H</i>pv <i>K</i>nowledge (THinK) questionnaire: a reliability and validity study on a sample of women living in Sicily (southern-Italy).PMC6511389Spera AGuarneri MFMatranga DNoto MGuarneri RSerra GPivetti ALumia CArculeo VMfalseThe vaccina<i>T</i>ion & <i>H</i>pv <i>K</i>nowledge (THinK) questionnaire: a reliability and validity study on a sample of women living in Sicily (southern-Italy).<h4>Objective</h4>The aim of this study was to introduce the VaccinaTion & Hpv Knowledge (THinK) questionnaire to assess knowledge about human papillomavirus (HPV) and attitude to HPV-vaccination. Its reliability and validity was demonstrated in a sample of women living in Sicily (southern Italy).<h4>Methods</h4>A cross-sectional survey was conducted on a sample of 220 women at the "Paolo Giaccone" University Hospital in Palermo (Sicily), aged 18-61. Data were analyzed through Cronbach's alpha and exploratory factor analysis, followed by a structural equation model with measurement component. The two-level data structure was explicitly considered.<h4>Results</h4>Three dimensions were found: "knowledge of HPV infection (kHPV), "Attitude to be vaccinated against HPV (aHPV)" and "Knowledge ab2019-01-01T00:00:00Z20192025-05-29T20:21:54.531Z2025-05-29T20:21:54.531ZS-EPMC65113893111906310.7717/peerj.6254