{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wassing R"],"funding":["Bial Foundation","VICI","European Research Council","Dutch Research Council (NWO)","ZonMw","INSOMNIA BEAT IT"],"pagination":["1783-1796"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6536850"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["142(6)"],"pubmed_abstract":["Studies suggest that sleep supports persistent changes in the neuronal representation of emotional experiences such that they are remembered better and less distressful when recalled than when they were first experienced. It is conceivable that sleep fragmentation by arousals, a key characteristic of insomnia disorder, could hamper the downregulation of distress. In this study, we sought further support for the idea that insomnia disorder may involve a lasting deficiency to downregulate emotional distress. We used functional MRI in insomnia disorder (n = 27) and normal sleepers (n = 30) to identify how brain activation differs between novel and relived self-conscious emotions. We evaluated whether brain activity elicited by reliving emotional memories from the distant past resembles the ac"],"journal":["Brain : a journal of neurology"],"pubmed_title":["Haunted by the past: old emotions remain salient in insomnia disorder."],"pmcid":["PMC6536850"],"funding_grant_id":["ERC-2016-PoC-737634","16.561.0001","453.07.001","253/2012","ERC-ADG-2014–671084 INSOMNIA","737634"],"pubmed_authors":["Schalkwijk F","Wassing R","Lakbila-Kamal O","Ramautar JR","Talamini LM","Van Someren EJW","Mutsaerts HJMM","Stoffers D"],"additional_accession":[]},"is_claimable":false,"name":"Haunted by the past: old emotions remain salient in insomnia disorder.","description":"Studies suggest that sleep supports persistent changes in the neuronal representation of emotional experiences such that they are remembered better and less distressful when recalled than when they were first experienced. It is conceivable that sleep fragmentation by arousals, a key characteristic of insomnia disorder, could hamper the downregulation of distress. In this study, we sought further support for the idea that insomnia disorder may involve a lasting deficiency to downregulate emotional distress. We used functional MRI in insomnia disorder (n = 27) and normal sleepers (n = 30) to identify how brain activation differs between novel and relived self-conscious emotions. We evaluated whether brain activity elicited by reliving emotional memories from the distant past resembles the ac","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Jun","modification":"2025-05-29T20:17:32.675Z","creation":"2025-05-29T20:17:32.675Z"},"accession":"S-EPMC6536850","cross_references":{"pubmed":["31135050"],"doi":["10.1093/brain/awz089"]}}