{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Han J"],"funding":["National Natural Science Foundation of China"],"pagination":["E1828"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6539882"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["24(9)"],"pubmed_abstract":["This work discloses a new procedure for the resolution of commercially available racemic rimantadine hydrochloride to enantiomerically pure (S)-rimantadine using (R)-phenoxypropionic acid as a recyclable resolving reagent. Good chemical yields, operational ease, and low-cost structure underscore the preparative value of this method for the production of enantiomerically pure rimantadine for medicinal or synthetic studies."],"journal":["Molecules (Basel, Switzerland)"],"pubmed_title":["Optical Resolution of Rimantadine."],"pmcid":["PMC6539882"],"funding_grant_id":["21761132021 and 21606133"],"pubmed_authors":["Izawa K","Sato T","Takeda R","Moriwaki H","Han J","Abe H","Soloshonok VA"],"additional_accession":[]},"is_claimable":false,"name":"Optical Resolution of Rimantadine.","description":"This work discloses a new procedure for the resolution of commercially available racemic rimantadine hydrochloride to enantiomerically pure (S)-rimantadine using (R)-phenoxypropionic acid as a recyclable resolving reagent. Good chemical yields, operational ease, and low-cost structure underscore the preparative value of this method for the production of enantiomerically pure rimantadine for medicinal or synthetic studies.","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 May","modification":"2025-04-04T09:36:08.493Z","creation":"2019-07-01T13:56:23Z"},"accession":"S-EPMC6539882","cross_references":{"pubmed":["31083636"],"doi":["10.3390/molecules24091828"]}}