{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["6(1)"],"submitter":["Frank D"],"funding":["Edwards Lifesciences"],"pubmed_abstract":["<h4>Background</h4>Patients with severe aortic stenosis (AS) have a reduced life expectancy and quality of life (QoL), owing to advanced age and the presence of multiple comorbidities. Currently, there is no AS-specific QoL measurement tool, which prevents an accurate assessment of how this chronic condition and its treatment affect patients. The Toronto Aortic Stenosis Quality of Life Questionnaire (TASQ) was developed in order to address this deficiency.<h4>Methods</h4>The present trial protocol was designed to enable validation of the TASQ, which has been produced in five languages (English, French, German, Italian and Spanish) to increase usability. Patients with severe AS who are undergoing surgical aortic valve replacement (SAVR) or transcatheter aortic valve implantation (TAVI) will"],"journal":["Open heart"],"pagination":["e001008"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6546188"],"repository":["biostudies-literature"],"pubmed_title":["Trial protocol for the validation of the 'Toronto Aortic Stenosis Quality of Life (TASQ) Questionnaire' in patients undergoing surgical aortic valve replacement (SAVR) or transfemoral (TF) transcatheter aortic valve implantation (TAVI): the TASQ registry."],"pmcid":["PMC6546188"],"pubmed_authors":["Luske C","Romano M","Kurucova J","Cuenca Castillo JJ","Thoenes M","Kennon S","Bramlage P","Styra R","Ribichini FL","Frank D","Bonaros N","Himbert D","Lefevre T","Urena-Alcazar M","Stefano P","Garcia B","Di Mario C","Salgado-Fernandez J"],"additional_accession":[]},"is_claimable":false,"name":"Trial protocol for the validation of the 'Toronto Aortic Stenosis Quality of Life (TASQ) Questionnaire' in patients undergoing surgical aortic valve replacement (SAVR) or transfemoral (TF) transcatheter aortic valve implantation (TAVI): the TASQ registry.","description":"<h4>Background</h4>Patients with severe aortic stenosis (AS) have a reduced life expectancy and quality of life (QoL), owing to advanced age and the presence of multiple comorbidities. Currently, there is no AS-specific QoL measurement tool, which prevents an accurate assessment of how this chronic condition and its treatment affect patients. The Toronto Aortic Stenosis Quality of Life Questionnaire (TASQ) was developed in order to address this deficiency.<h4>Methods</h4>The present trial protocol was designed to enable validation of the TASQ, which has been produced in five languages (English, French, German, Italian and Spanish) to increase usability. Patients with severe AS who are undergoing surgical aortic valve replacement (SAVR) or transcatheter aortic valve implantation (TAVI) will","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019","modification":"2026-06-08T06:51:18.868Z","creation":"2026-06-08T03:14:35.179Z"},"accession":"S-EPMC6546188","cross_references":{"pubmed":["31218003"],"doi":["10.1136/openhrt-2019-001008"]}}