biostudies-literatureZahniser ENINDS NIH HHS1786-1793https://www.ebi.ac.uk/biostudies/studies/S-EPMC6551992biostudies-literatureUnknown36(11)Mental health problems, such as depression and anxiety, are often associated with functional limitations after traumatic brain injury (TBI), prompting researchers to explore which of these TBI-related sequelae tends to precede the other. Past studies among patients with injuries ranging in severity have predominantly reported that functional impairments predict subsequent psychological concerns, rather than the other way around; however, it remains unclear whether this directionality holds for individuals with mild TBI (mTBI). The present study utilized a cross-lagged panel design within a structural equation modeling analytical framework to explore the longitudinal relationships of symptoms of depression and anxiety to functional status among 717 adult mTBI patients, with assessments occuJournal of neurotraumaThe Temporal Relationship of Mental Health Problems and Functional Limitations following mTBI: A TRACK-TBI and TED Study.PMC6551992U01 NS086090Feeser VRCrawford KMcCrea MTaylor SGonzalez LNoel FMadden COkonkwo DGiacino JSchnyer DWang KYue JDuhaime ACSander ASatris GRoss Bullock MFerguson ABadjatia NAdeoye OJain SGopinath SSherer MNelson LDMachamer JEEllenbogen RPuccio AVassar MBodien YToga AMukherjee PPerl DPalacios ERabinowitz MKramer JManley GTBoase KClaude Hemphill JStein MBForeman BLindsell CZafonte RGullapalli RYuh ECorrigan JDDiaz-Arrastia RZahniser EGardner RDikmen SSChesnut RKreitzer NSeabury SGaudette EVespa PMcAllister TLevin HKorley FMartin ARobertson CRosand JMerchant RValadka ATemkin NRTRACK-TBI InvestigatorsHotz GfalseThe Temporal Relationship of Mental Health Problems and Functional Limitations following mTBI: A TRACK-TBI and TED Study.Mental health problems, such as depression and anxiety, are often associated with functional limitations after traumatic brain injury (TBI), prompting researchers to explore which of these TBI-related sequelae tends to precede the other. Past studies among patients with injuries ranging in severity have predominantly reported that functional impairments predict subsequent psychological concerns, rather than the other way around; however, it remains unclear whether this directionality holds for individuals with mild TBI (mTBI). The present study utilized a cross-lagged panel design within a structural equation modeling analytical framework to explore the longitudinal relationships of symptoms of depression and anxiety to functional status among 717 adult mTBI patients, with assessments occu2019-01-01T00:00:00Z2019 Jun2025-04-18T22:10:46.735Z2020-06-04T07:07:39ZS-EPMC65519923054313810.1089/neu.2018.6172