biostudies-literatureUnknown13Bourika K<h4>Objective</h4>This study was designed to reevaluate and improve the quality and safety of the chemotherapy preparation in a Central Chemotherapy Preparation Unit of a Public Hospital.<h4>Methods</h4>A failure modes, effects, and criticality analysis (FMECA) was conducted by a multidisciplinary team. All potential failure modes at each stage of the chemotherapy preparation were recorded, and the associated risks were scored for their severity, occurrence, and detectability with a risk priority number (RPN). Corrective actions were suggested, and new RPNs were estimated for the modified process.<h4>Results</h4>Failure modes, effects, and criticality analysis and priority matrix construction, revealed that the partial compliance of Unit's premises with international standards (RPN<sub>staClinical Medicine Insights. Oncology1179554919852933https://www.ebi.ac.uk/biostudies/studies/S-EPMC6558536biostudies-literatureImprovement of Chemotherapy Solutions Production Procedure in a Hospital Central Chemotherapy Preparation Unit: A Systematic Risk Assessment to Prevent Avoidable Harm in Cancer Patients.PMC6558536Tsiata EBourika KVicha AKalofonos HAvgoustakis KPanagi ZPapadimitriou EKoutras AfalseImprovement of Chemotherapy Solutions Production Procedure in a Hospital Central Chemotherapy Preparation Unit: A Systematic Risk Assessment to Prevent Avoidable Harm in Cancer Patients.<h4>Objective</h4>This study was designed to reevaluate and improve the quality and safety of the chemotherapy preparation in a Central Chemotherapy Preparation Unit of a Public Hospital.<h4>Methods</h4>A failure modes, effects, and criticality analysis (FMECA) was conducted by a multidisciplinary team. All potential failure modes at each stage of the chemotherapy preparation were recorded, and the associated risks were scored for their severity, occurrence, and detectability with a risk priority number (RPN). Corrective actions were suggested, and new RPNs were estimated for the modified process.<h4>Results</h4>Failure modes, effects, and criticality analysis and priority matrix construction, revealed that the partial compliance of Unit's premises with international standards (RPN<sub>sta2019-01-01T00:00:00Z20192025-04-04T21:28:07.32Z2019-07-24T07:14:18ZS-EPMC65585363121769910.1177/1179554919852933