{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Nishimura M"],"funding":["the Project of the NARO Bio-oriented Technology Research Advancement Institution (the special scheme project on regional developing strategy)."],"pagination":["E1177"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6566250"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(5)"],"pubmed_abstract":["Tomato (<i>Solanum lycopersicum</i>) is a rich source of lycopene, a carotenoid that confers various positive biological effects such as improved lipid metabolism. Here, we conducted a randomized, double-blind, placebo-controlled, parallel-group comparative study to investigate the effects of regular and continuous intake of a new high-lycopene tomato, a variety named PR-7, for 12 weeks, based on 74 healthy Japanese subjects with low-density lipoprotein cholesterol (LDL-C) levels ≥120 to <160 mg/dL. The subjects were randomly assigned to either the high-lycopene tomato or placebo (lycopene-free tomato) group. Each subject in the high-lycopene group ingested 50 g of semidried PR-7 (lycopene, 22.0-27.8 mg/day) each day for 12 weeks, while subjects in the placebo group ingested placebo semidr"],"journal":["Nutrients"],"pubmed_title":["Effect of 12-Week Daily Intake of the High-Lycopene Tomato (<i>Solanum Lycopersicum</i>), A Variety Named \"PR-7\", on Lipid Metabolism: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study."],"pmcid":["PMC6566250"],"funding_grant_id":["16797811"],"pubmed_authors":["Ishikawa-Takano Y","Nishimura M","Nishihira J","Tominaga N","Maeda-Yamamoto M"],"additional_accession":[]},"is_claimable":false,"name":"Effect of 12-Week Daily Intake of the High-Lycopene Tomato (<i>Solanum Lycopersicum</i>), A Variety Named \"PR-7\", on Lipid Metabolism: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study.","description":"Tomato (<i>Solanum lycopersicum</i>) is a rich source of lycopene, a carotenoid that confers various positive biological effects such as improved lipid metabolism. Here, we conducted a randomized, double-blind, placebo-controlled, parallel-group comparative study to investigate the effects of regular and continuous intake of a new high-lycopene tomato, a variety named PR-7, for 12 weeks, based on 74 healthy Japanese subjects with low-density lipoprotein cholesterol (LDL-C) levels ≥120 to <160 mg/dL. The subjects were randomly assigned to either the high-lycopene tomato or placebo (lycopene-free tomato) group. Each subject in the high-lycopene group ingested 50 g of semidried PR-7 (lycopene, 22.0-27.8 mg/day) each day for 12 weeks, while subjects in the placebo group ingested placebo semidr","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 May","modification":"2025-06-01T02:54:53.426Z","creation":"2025-06-01T02:54:53.426Z"},"accession":"S-EPMC6566250","cross_references":{"pubmed":["31130668"],"doi":["10.3390/nu11051177"]}}