biostudies-literatureOlsen TNovo Nordisk FoundationRegion of Southern DenmarkDanish Heart AssociationNovo Nordisk Fonden1862-1869https://www.ebi.ac.uk/biostudies/studies/S-EPMC6568207biostudies-literatureUnknown40(23)<h4>Aims</h4>Device-related infection (DRI) is a severe complication to cardiac implantable electronic devices (CIED) therapy. Device-related infection incidence and its risk factors differ between previous studies. We aimed to define the long-term incidence and incidence rates of DRI for different types of CIEDs in the complete Danish device-cohort and identify patient-, operation- and device-related risk factors for DRI.<h4>Methods and results</h4>From the Danish Pacemaker (PM) and implantable cardioverter-defibrillator (ICD) Register, we included consecutive Danish patients undergoing CIED implantation or reoperation from January 1982 to April 2018, resulting in 97 750 patients, 128 045 operations and follow-up of in total 566 275 device years (DY). We identified 1827 DRI causing deviceEuropean heart journalIncidence of device-related infection in 97 750 patients: clinical data from the complete Danish device-cohort (1982-2018).PMC656820716/36792NNF16OC001865815-R99-A5950-22895Johansen JBPhilbert BTThogersen AMNielsen JCOlsen TJorgensen ODfalseIncidence of device-related infection in 97 750 patients: clinical data from the complete Danish device-cohort (1982-2018).<h4>Aims</h4>Device-related infection (DRI) is a severe complication to cardiac implantable electronic devices (CIED) therapy. Device-related infection incidence and its risk factors differ between previous studies. We aimed to define the long-term incidence and incidence rates of DRI for different types of CIEDs in the complete Danish device-cohort and identify patient-, operation- and device-related risk factors for DRI.<h4>Methods and results</h4>From the Danish Pacemaker (PM) and implantable cardioverter-defibrillator (ICD) Register, we included consecutive Danish patients undergoing CIED implantation or reoperation from January 1982 to April 2018, resulting in 97 750 patients, 128 045 operations and follow-up of in total 566 275 device years (DY). We identified 1827 DRI causing device2019-01-01T00:00:00Z2019 Jun2025-04-04T13:05:21.176Z2019-07-24T07:18:29ZS-EPMC65682073115564710.1093/eurheartj/ehz316