{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Brigham EP"],"funding":["NCATS NIH HHS","NIEHS NIH HHS","NHLBI NIH HHS"],"pagination":["1478-1486"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6580674"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["199(12)"],"pubmed_abstract":["<b>Rationale:</b> Higher indoor particulate matter (PM) concentrations are linked with increased asthma morbidity. Dietary intake of fatty acids, also linked with asthma outcomes, may influence this relationship. <b>Objectives:</b> To determine the relationship between omega-3 and omega-6 fatty acid intake and pediatric asthma morbidity, and the association between fatty acid intake and strength of indoor, PM-related asthma symptoms, albuterol use, and systemic inflammation. <b>Methods:</b> Analyses included 135 children with asthma enrolled in the AsthmaDIET Study. At baseline, 3 months, and 6 months, data included: week-long average home indoor concentration of PM ≤2.5 μm in aerodynamic diameter and PM ≤10 μm in aerodynamic diameter, dietary intake of omega-3 and omega-6 fatty acids, dai"],"journal":["American journal of respiratory and critical care medicine"],"pubmed_title":["Omega-3 and Omega-6 Intake Modifies Asthma Severity and Response to Indoor Air Pollution in Children."],"pmcid":["PMC6580674"],"funding_grant_id":["KL2 TR001077","P50 ES015903","K24 ES021098","T32 HL072748","P50 ES018176","P01 ES018176","K23 ES029105"],"pubmed_authors":["Rice J","Koehler K","Woo H","Brigham EP","Bose S","Sharma S","Romero K","Hansel NN","Koch A","Kolahdooz F","Hanson C","McCormack M","Vulcain T","Wu T","Diette G"],"additional_accession":[]},"is_claimable":false,"name":"Omega-3 and Omega-6 Intake Modifies Asthma Severity and Response to Indoor Air Pollution in Children.","description":"<b>Rationale:</b> Higher indoor particulate matter (PM) concentrations are linked with increased asthma morbidity. Dietary intake of fatty acids, also linked with asthma outcomes, may influence this relationship. <b>Objectives:</b> To determine the relationship between omega-3 and omega-6 fatty acid intake and pediatric asthma morbidity, and the association between fatty acid intake and strength of indoor, PM-related asthma symptoms, albuterol use, and systemic inflammation. <b>Methods:</b> Analyses included 135 children with asthma enrolled in the AsthmaDIET Study. At baseline, 3 months, and 6 months, data included: week-long average home indoor concentration of PM ≤2.5 μm in aerodynamic diameter and PM ≤10 μm in aerodynamic diameter, dietary intake of omega-3 and omega-6 fatty acids, dai","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Jun","modification":"2025-04-19T10:43:18.48Z","creation":"2022-02-09T15:01:17.267Z"},"accession":"S-EPMC6580674","cross_references":{"pubmed":["30922077"],"doi":["10.1164/rccm.201808-1474OC","10.1164/rccm.201808-1474oc"]}}