{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ogran A"],"funding":["Israel Science Foundation"],"pagination":["e00512-19"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6581183"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["85(13)"],"pubmed_abstract":["Microbial ecosystems tightly associated with a eukaryotic host are widespread in nature. The genetic and metabolic networks of the eukaryotic hosts and the associated microbes have coevolved to form a symbiotic relationship. Both the Gram-positive Bacillus subtilis and the Gram-negative Serratia plymuthica can form biofilms on plant roots and thus can serve as a model system for the study of interspecies interactions in a host-associated ecosystem. We found that B. subtilis biofilms expand collectively and asymmetrically toward S. plymuthica, while expressing a nonribosomal antibiotic bacillaene and an extracellular protease. As a result, B. subtilis biofilms outcompeted S. plymuthica for successful colonization of the host. Strikingly, the plant host was able to enhance the efficiency of "],"journal":["Applied and environmental microbiology"],"pubmed_title":["The Plant Host Induces Antibiotic Production To Select the Most-Beneficial Colonizers."],"pmcid":["PMC6581183"],"funding_grant_id":["119/2016","152/1 Icore"],"pubmed_authors":["Jain R","Bucher T","Keren-Paz A","Kolodkin-Gal I","Gilhar O","Ogran A","Yardeni EH"],"additional_accession":[]},"is_claimable":false,"name":"The Plant Host Induces Antibiotic Production To Select the Most-Beneficial Colonizers.","description":"Microbial ecosystems tightly associated with a eukaryotic host are widespread in nature. The genetic and metabolic networks of the eukaryotic hosts and the associated microbes have coevolved to form a symbiotic relationship. Both the Gram-positive Bacillus subtilis and the Gram-negative Serratia plymuthica can form biofilms on plant roots and thus can serve as a model system for the study of interspecies interactions in a host-associated ecosystem. We found that B. subtilis biofilms expand collectively and asymmetrically toward S. plymuthica, while expressing a nonribosomal antibiotic bacillaene and an extracellular protease. As a result, B. subtilis biofilms outcompeted S. plymuthica for successful colonization of the host. Strikingly, the plant host was able to enhance the efficiency of ","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Jul","modification":"2025-05-29T22:06:14.098Z","creation":"2025-05-29T22:06:14.098Z"},"accession":"S-EPMC6581183","cross_references":{"pubmed":["31003984"],"doi":["10.1128/AEM.00512-19","10.1128/aem.00512-19"]}}