{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Katanga J"],"funding":["Danish International Development Agency"],"pagination":["e0218559"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6583973"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(6)"],"pubmed_abstract":["<h4>Objective</h4>To examine the test performance of careHPV, Hybrid Capture2 (HC2) and visual inspection with acetic acid (VIA) for detection of cytologically diagnosed high-grade cervical lesions or cancer (HSIL+).<h4>Design</h4>Cross-sectional study.<h4>Setting</h4>Ocean Road Cancer Institute (ORCI) and Kilimanjaro Christian Medical Center (KCMC), Tanzania.<h4>Population</h4>Women attending routine cervical cancer screening.<h4>Method</h4>We enrolled 4080 women (25-60 years) in the study. The women were interviewed on lifestyle habits, and tested for HIV. A cervical specimen for careHPV testing (performed at ORCI and KCMC), and a liquid-based cytology sample for HPV DNA detection using HC2 (performed at Tuebingen University Hospital, Germany) and for cytology assessment (performed at Ve"],"journal":["PloS one"],"pubmed_title":["Performance of careHPV, hybrid capture 2 and visual inspection with acetic acid for detection of high-grade cervical lesion in Tanzania: A cross-sectional study."],"pmcid":["PMC6583973"],"funding_grant_id":["14-TAN-P02"],"pubmed_authors":["Manongi R","Waldstrom M","Pembe AB","Mwaiselage J","Rasch V","Iftner T","Katanga J","Wu CS","Kjaer SK"],"additional_accession":[]},"is_claimable":false,"name":"Performance of careHPV, hybrid capture 2 and visual inspection with acetic acid for detection of high-grade cervical lesion in Tanzania: A cross-sectional study.","description":"<h4>Objective</h4>To examine the test performance of careHPV, Hybrid Capture2 (HC2) and visual inspection with acetic acid (VIA) for detection of cytologically diagnosed high-grade cervical lesions or cancer (HSIL+).<h4>Design</h4>Cross-sectional study.<h4>Setting</h4>Ocean Road Cancer Institute (ORCI) and Kilimanjaro Christian Medical Center (KCMC), Tanzania.<h4>Population</h4>Women attending routine cervical cancer screening.<h4>Method</h4>We enrolled 4080 women (25-60 years) in the study. The women were interviewed on lifestyle habits, and tested for HIV. A cervical specimen for careHPV testing (performed at ORCI and KCMC), and a liquid-based cytology sample for HPV DNA detection using HC2 (performed at Tuebingen University Hospital, Germany) and for cytology assessment (performed at Ve","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019","modification":"2025-05-29T21:05:11.616Z","creation":"2025-05-29T21:05:11.616Z"},"accession":"S-EPMC6583973","cross_references":{"pubmed":["31216333"],"doi":["10.1371/journal.pone.0218559"]}}