{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Scully RR"],"funding":["NASA | Johnson Space Center","NASA Human Research Program"],"pagination":["17"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6584569"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["5"],"pubmed_abstract":["Acute exposure to carbon dioxide (CO<sub>2</sub>) concentrations below those found on the International Space Station are reported to deteriorate complex decision-making. Effective decision-making is critical to human spaceflight, especially during an emergency response. Therefore, effects of acutely elevated CO<sub>2</sub> on decision-making competency and various cognitive domains were assessed in astronaut-like subjects by the <i>Strategic Management Simulation</i> (SMS) and <i>Cognition</i> test batteries. The double-blind cross-over study included 22 participants at the Johnson Space Center randomly assigned to one of four groups. Each group was exposed to a different sequence of four concentrations of CO<sub>2</sub> (600, 1200, 2500, 5000 ppm). Subjects performed <i>Cognition</i> bef"],"journal":["NPJ microgravity"],"pubmed_title":["Effects of acute exposures to carbon dioxide on decision making and cognition in astronaut-like subjects."],"pmcid":["PMC6584569"],"funding_grant_id":["NNX14AH98G"],"pubmed_authors":["Nasrini J","Gur RC","Satish U","Basner M","Lam CW","Alexander DJ","Scully RR","Hermosillo E","Moore T","Ryder VE"],"additional_accession":[]},"is_claimable":false,"name":"Effects of acute exposures to carbon dioxide on decision making and cognition in astronaut-like subjects.","description":"Acute exposure to carbon dioxide (CO<sub>2</sub>) concentrations below those found on the International Space Station are reported to deteriorate complex decision-making. Effective decision-making is critical to human spaceflight, especially during an emergency response. Therefore, effects of acutely elevated CO<sub>2</sub> on decision-making competency and various cognitive domains were assessed in astronaut-like subjects by the <i>Strategic Management Simulation</i> (SMS) and <i>Cognition</i> test batteries. The double-blind cross-over study included 22 participants at the Johnson Space Center randomly assigned to one of four groups. Each group was exposed to a different sequence of four concentrations of CO<sub>2</sub> (600, 1200, 2500, 5000 ppm). Subjects performed <i>Cognition</i> bef","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019","modification":"2025-05-29T21:06:26.458Z","creation":"2025-05-29T21:06:26.458Z"},"accession":"S-EPMC6584569","cross_references":{"pubmed":["31240239"],"doi":["10.1038/s41526-019-0071-6"]}}