{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Isaksson J"],"funding":["The Swedish Order of Freemasons","Stockholm Brain Institute","The Jeansson Foundation","Vetenskapsrådet","Svenska Forskningsrådet Formas","Kempe-Carlgrenska Foundation","FORTE","The Innovative Medicines Initiative Joint Undertaking","The Swedish Foundation for Strategic Research","Jerring Foundation","Queen Silvia Jubilee Fund","Sunnderdahls Handikappsfond","PRIMA Child and Adult Psychiatry","Hjärnfonden","The Pediatric Research Foundation at Astrid Lindgren Children's Hospita","Stiftelsen Solstickan","Autism and Asperger Association Stockholm","VINNOVA"],"pagination":["2838-2848"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6606667"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["49(7)"],"pubmed_abstract":["Alterations in social cognition (SC) are hypothesized to underlie social communication and interaction challenges in autism spectrum disorder (ASD). The aetiological underpinnings driving this association remain unclear. We examined SC in 196 twins with ASD, other neurodevelopmental disorders or typical development using the naturalistic Movie for the Assessment of Social Cognition. Autism and its severity were assessed with the Autism Diagnostic Observation Schedule-2, and autistic traits with the Social Responsiveness Scale-2. Using within twin-pair regression models, controlling for age, sex, IQ, and unmeasured familial confounders such as genetic background and shared-environment, SC correlated with ASD diagnosis, autism severity, and autistic traits. Our findings highlight the importa"],"journal":["Journal of autism and developmental disorders"],"pubmed_title":["Social Cognition in Autism and Other Neurodevelopmental Disorders: A Co-twin Control Study."],"pmcid":["PMC6606667"],"funding_grant_id":["115300"],"pubmed_authors":["Kuja-Halkola R","Cauvet E","Lundin K","Neufeld J","Willfors C","Isaksson J","Bolte S","Van't Westeinde A"],"additional_accession":[]},"is_claimable":false,"name":"Social Cognition in Autism and Other Neurodevelopmental Disorders: A Co-twin Control Study.","description":"Alterations in social cognition (SC) are hypothesized to underlie social communication and interaction challenges in autism spectrum disorder (ASD). The aetiological underpinnings driving this association remain unclear. We examined SC in 196 twins with ASD, other neurodevelopmental disorders or typical development using the naturalistic Movie for the Assessment of Social Cognition. Autism and its severity were assessed with the Autism Diagnostic Observation Schedule-2, and autistic traits with the Social Responsiveness Scale-2. Using within twin-pair regression models, controlling for age, sex, IQ, and unmeasured familial confounders such as genetic background and shared-environment, SC correlated with ASD diagnosis, autism severity, and autistic traits. Our findings highlight the importa","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Jul","modification":"2025-04-05T10:43:30.815Z","creation":"2019-07-25T07:02:55Z"},"accession":"S-EPMC6606667","cross_references":{"pubmed":["30972652"],"doi":["10.1007/s10803-019-04001-4"]}}