biostudies-literatureAyer SKDuke UniversityNational Institute of General Medical SciencesNIGMS NIH HHS3508-3523https://www.ebi.ac.uk/biostudies/studies/S-EPMC6656367biostudies-literatureUnknown84(6)Owing to the pervasiveness of hydroxyl groups in natural isolates, alcohol derivatives are alluring directing groups. Herein, an alcohol-derived sulfamate ester guides the light-initiated xanthylation of primary, secondary, or tertiary centers. This process enables formal directed deuteration, azidation, thiolation, and vinylation reactions.The Journal of organic chemistrySulfamate Esters Guide C(3)-Selective Xanthylation of Alkanes.PMC6656367R35GM128741-01R35 GM128741Ayer SKRoizen JLfalseSulfamate Esters Guide C(3)-Selective Xanthylation of Alkanes.Owing to the pervasiveness of hydroxyl groups in natural isolates, alcohol derivatives are alluring directing groups. Herein, an alcohol-derived sulfamate ester guides the light-initiated xanthylation of primary, secondary, or tertiary centers. This process enables formal directed deuteration, azidation, thiolation, and vinylation reactions.2019-01-01T00:00:00Z2019 Mar2024-11-20T23:54:48.264Z2020-10-29T12:10:16ZS-EPMC66563673077956110.1021/acs.joc.9b00105