{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Haller G"],"funding":["Monash University","National Institute for Health Research (NIHR)"],"pagination":["228-237"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6676244"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["123(2)"],"pubmed_abstract":["Background
Clinical indicators are powerful tools to quantify the safety and quality of patient care. Their validity is often unclear and definitions extremely heterogeneous. As part of the International Standardised Endpoints in Perioperative Medicine (StEP) initiative, this study aimed to derive a set of standardised and valid clinical outcome indicators for use in perioperative clinical trials.Methods
We identified clinical indicators via a systematic review of the anaesthesia and perioperative medicine literature (PubMed/OVID, EMBASE, and Cochrane Library). We performed a three-stage Delphi consensus-gaining process that involved 54 clinician-researchers worldwide. Indicators were first shortlisted and the most suitable definitions for evaluation of quality and safety i"],"journal":["British journal of anaesthesia"],"pubmed_title":["Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine initiative: clinical indicators."],"pmcid":["PMC6676244"],"funding_grant_id":["DRF-2015-08-023","NF-SI-0617-10170"],"pubmed_authors":["De Oliveira GS","Futier E","Lane-Fall M","Boney O","Nagele P","Wu C","Biccard B","Grocott M","Neuman M","Rasmussen L","Jamie Cooper D","Myles PS","Grocott H","Pelosi P","Haller G","Beattie S","Corcoran T","Howell S","van Klei W","Jayarajah M","Cyna A","Gottumukkala V","Richards T","Chan M","Myles P","Fleisher L","Riedel B","Pace N","Moller A","Moonesinghe R","Billings J","Blazeby J","Lalu M","Mythen M","McIlroy D","van Dijk D","Buggy D","Karkouti K","Bellomo R","Alkhaffaf B","Cook T","Sessler D","Eriksson L","Grocott MPW","Pearse R","Creagh-Brown B","Fleisher LA","Scott D","Johnson M","Shaw A","Dieleman S","Diouf E","Gabreu M","Miller T","Canet J","Stevenson N","Story D","Morris S","Kurz A","Gan TJ","Jensen M","Murphy M","Evered L","Botti M","Lamy A","George R","Schultz M","Abbott T","Prowle J","Eckenhoff R","Landoni G","Bampoe S","Cabrini L","Jackson S","Bartoszko J","Sneyd R","Gruen R","Shulman M","StEP-COMPAC Group","Kalkman C","Wijeysundera D","Silbert B","Kehlet H","Klein A","Leslie K","Gin T","Nilsson U","Tramer M","Cooper JDJ","Peyton P","Mazer D","Short T"],"additional_accession":[]},"is_claimable":false,"name":"Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine initiative: clinical indicators.","description":"Background
Clinical indicators are powerful tools to quantify the safety and quality of patient care. Their validity is often unclear and definitions extremely heterogeneous. As part of the International Standardised Endpoints in Perioperative Medicine (StEP) initiative, this study aimed to derive a set of standardised and valid clinical outcome indicators for use in perioperative clinical trials.Methods
We identified clinical indicators via a systematic review of the anaesthesia and perioperative medicine literature (PubMed/OVID, EMBASE, and Cochrane Library). We performed a three-stage Delphi consensus-gaining process that involved 54 clinician-researchers worldwide. Indicators were first shortlisted and the most suitable definitions for evaluation of quality and safety i","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Aug","modification":"2025-04-04T20:10:26.891Z","creation":"2019-08-12T07:05:48Z"},"accession":"S-EPMC6676244","cross_references":{"pubmed":["31128879"],"doi":["10.1016/j.bja.2019.04.041"]}}