{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Timmons JA"],"funding":["Medical Research Council","National Institute for Health Research (NIHR)"],"pagination":["152"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6676519"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(1)"],"pubmed_abstract":["Jacob and Speed did not identify even a single example of a '150-gene-set' that was statistically significant at classifying Alzheimer's disease (AD) samples, or age in independent studies. We attempt to clarify the various misunderstandings, below."],"journal":["Genome biology"],"pubmed_title":["A statistical and biological response to an informatics appraisal of healthy aging gene signatures."],"pmcid":["PMC6676519"],"funding_grant_id":["G1100015","NF-SI-0616-10042"],"pubmed_authors":["Howard R","Timmons JA","Sood S","Crossland H","Phillips B","Gallagher IJ","Atherton PJ","Kraus WE"],"additional_accession":[]},"is_claimable":false,"name":"A statistical and biological response to an informatics appraisal of healthy aging gene signatures.","description":"Jacob and Speed did not identify even a single example of a '150-gene-set' that was statistically significant at classifying Alzheimer's disease (AD) samples, or age in independent studies. We attempt to clarify the various misunderstandings, below.","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Aug","modification":"2026-05-07T01:46:25.972Z","creation":"2026-04-07T22:28:05.767Z"},"accession":"S-EPMC6676519","cross_references":{"pubmed":["31375147"],"doi":["10.1186/s13059-019-1734-z"]}}