{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Dam V"],"funding":["Dutch ZON","British Heart Foundation","Cancer Research UK","Hellenic Health Foundation","UK National Institute of Health Research","European Union Framework 7","Dutch Prevention Funds","FIS","World Cancer Research Fund","Stavros Niarchos Foundation","European Research Council","Medical Research Council","National Institute for Health Research (NIHR)","Swedish Cancer Society","Health Research Fund","Dutch Heart Foundation","Dutch Ministry of Public Health, Welfare and Sports","Danish Cancer Society","LK Research Funds","Novo Nordisk Fonden","Wellcome Trust"],"pagination":["1275-1285"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6693816"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["48(4)"],"pubmed_abstract":["<h4>Background</h4>Earlier age at menopause has been associated with increased risk of coronary heart disease (CHD), but the shape of association and role of established cardiovascular risk factors remain unclear. Therefore, we examined the associations between menopausal characteristics and CHD risk; the shape of the association between age at menopause and CHD risk; and the extent to which these associations are explained by established cardiovascular risk factors.<h4>Methods</h4>We used data from EPIC-CVD, a case-cohort study, which includes data from 23 centres from 10 European countries. We included only women, of whom 10 880 comprise the randomly selected sub-cohort, supplemented with 4522 cases outside the sub-cohort. We conducted Prentice-weighted Cox proportional hazards regressio"],"journal":["International journal of epidemiology"],"pubmed_title":["Association of menopausal characteristics and risk of coronary heart disease: a pan-European case-cohort analysis."],"pmcid":["PMC6693816"],"funding_grant_id":["268834","NF-SI-0617-10149","SP/09/002","RG/18/13/33946","204623/Z/16/Z","HDR-9004","NF-SI-0617-10113","2013T083","MC_UU_12015/1","RG/08/014","MR/L003120/1","MR/P014550/1","RG/13/13/30194","G0800270","HEALTH-F2-2012–279233","G0700463","NNF14OC0009819","MC_UU_00002/7","232997","RG13/13/30194"],"pubmed_authors":["La Vecchia C","Melander O","Boer JMA","van der Schouw YT","Burgess S","Trichopoulou A","Tjonneland A","Weiderpass E","Colorado-Yohar S","Gunter M","Engstrom G","Butterworth A","di Angelantonio E","Arriola L","Ferrari P","Peters SAE","Karakatsani A","Tumino R","Onland-Moret NC","Schuit E","Wood AM","Wennberg P","Key TJ","Groenwold RHH","Sweeting MJ","Holm M","Fortner RT","Nordendahl M","Oliver-Williams C","Matullo G","Boeing H","Clavel-Chapelon F","Dam V","Sieri S","Chirlaque MD","Danesh J","Moreno-Iribas C","Kuhn T","Wareham NJ","Riboli E","Masala G","Overvad K","Moons KGM","Salamanca-Fernandez E","Langenberg C","Panico S","Quiros JR","Tikk K","Verschuren WMM"],"additional_accession":[]},"is_claimable":false,"name":"Association of menopausal characteristics and risk of coronary heart disease: a pan-European case-cohort analysis.","description":"<h4>Background</h4>Earlier age at menopause has been associated with increased risk of coronary heart disease (CHD), but the shape of association and role of established cardiovascular risk factors remain unclear. Therefore, we examined the associations between menopausal characteristics and CHD risk; the shape of the association between age at menopause and CHD risk; and the extent to which these associations are explained by established cardiovascular risk factors.<h4>Methods</h4>We used data from EPIC-CVD, a case-cohort study, which includes data from 23 centres from 10 European countries. We included only women, of whom 10 880 comprise the randomly selected sub-cohort, supplemented with 4522 cases outside the sub-cohort. We conducted Prentice-weighted Cox proportional hazards regressio","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Aug","modification":"2025-04-04T19:04:52.847Z","creation":"2019-08-23T07:04:52Z"},"accession":"S-EPMC6693816","cross_references":{"pubmed":["30796459"],"doi":["10.1093/ije/dyz016"]}}