{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Uhlig C"],"funding":["Technische Universität Dresden (DE)/SLUB","Fresenius Kabi Deutschland AG"],"pagination":["156"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6698338"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["19(1)"],"pubmed_abstract":["<h4>Background</h4>Enhanced recovery after surgery programs (ERAS) using thoracic epidural anesthesia and perioperative patient conditioning with omega-3 fatty acids (n3FA), glucose control (GC) and on-demand fluid therapy, respectively, showed beneficial effects. In the MOFA- study these components were used together in patients undergoing colon or liver surgery. We hypothesized that the use of a perioperative MOFA program improves intestine function represented as time to the first postoperative bowel movement in adult patients compared to standard ERAS.<h4>Methods</h4>After BfArM and IRB approval 100 patients were enrolled in this prospective randomized controlled trial. All patients received ERAS therapy (control). In addition, the MOFA group received 0.2 g/kg fish oil (Omegaven®), pre"],"journal":["BMC anesthesiology"],"pubmed_title":["Effects of a metabolic optimized fast track concept (MOFA) on bowel function and recovery after surgery in patients undergoing elective colon or liver resection: a randomized controlled trial."],"pmcid":["PMC6698338"],"funding_grant_id":["Please see Funding declaration","IN-1502335"],"pubmed_authors":["Denz A","Heller AR","Seifert S","Uhlig C","Koch T","Rossel T"],"additional_accession":[]},"is_claimable":false,"name":"Effects of a metabolic optimized fast track concept (MOFA) on bowel function and recovery after surgery in patients undergoing elective colon or liver resection: a randomized controlled trial.","description":"<h4>Background</h4>Enhanced recovery after surgery programs (ERAS) using thoracic epidural anesthesia and perioperative patient conditioning with omega-3 fatty acids (n3FA), glucose control (GC) and on-demand fluid therapy, respectively, showed beneficial effects. In the MOFA- study these components were used together in patients undergoing colon or liver surgery. We hypothesized that the use of a perioperative MOFA program improves intestine function represented as time to the first postoperative bowel movement in adult patients compared to standard ERAS.<h4>Methods</h4>After BfArM and IRB approval 100 patients were enrolled in this prospective randomized controlled trial. All patients received ERAS therapy (control). In addition, the MOFA group received 0.2 g/kg fish oil (Omegaven®), pre","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Aug","modification":"2026-05-02T19:35:17.746Z","creation":"2019-08-26T07:03:18Z"},"accession":"S-EPMC6698338","cross_references":{"pubmed":["31421670"],"doi":["10.1186/s12871-019-0823-6"]}}