biostudies-literatureUhlig CTechnische Universität Dresden (DE)/SLUBFresenius Kabi Deutschland AG156https://www.ebi.ac.uk/biostudies/studies/S-EPMC6698338biostudies-literatureUnknown19(1)<h4>Background</h4>Enhanced recovery after surgery programs (ERAS) using thoracic epidural anesthesia and perioperative patient conditioning with omega-3 fatty acids (n3FA), glucose control (GC) and on-demand fluid therapy, respectively, showed beneficial effects. In the MOFA- study these components were used together in patients undergoing colon or liver surgery. We hypothesized that the use of a perioperative MOFA program improves intestine function represented as time to the first postoperative bowel movement in adult patients compared to standard ERAS.<h4>Methods</h4>After BfArM and IRB approval 100 patients were enrolled in this prospective randomized controlled trial. All patients received ERAS therapy (control). In addition, the MOFA group received 0.2 g/kg fish oil (Omegaven®), preBMC anesthesiologyEffects of a metabolic optimized fast track concept (MOFA) on bowel function and recovery after surgery in patients undergoing elective colon or liver resection: a randomized controlled trial.PMC6698338Please see Funding declarationIN-1502335Denz AHeller ARSeifert SUhlig CKoch TRossel TfalseEffects of a metabolic optimized fast track concept (MOFA) on bowel function and recovery after surgery in patients undergoing elective colon or liver resection: a randomized controlled trial.<h4>Background</h4>Enhanced recovery after surgery programs (ERAS) using thoracic epidural anesthesia and perioperative patient conditioning with omega-3 fatty acids (n3FA), glucose control (GC) and on-demand fluid therapy, respectively, showed beneficial effects. In the MOFA- study these components were used together in patients undergoing colon or liver surgery. We hypothesized that the use of a perioperative MOFA program improves intestine function represented as time to the first postoperative bowel movement in adult patients compared to standard ERAS.<h4>Methods</h4>After BfArM and IRB approval 100 patients were enrolled in this prospective randomized controlled trial. All patients received ERAS therapy (control). In addition, the MOFA group received 0.2 g/kg fish oil (Omegaven®), pre2019-01-01T00:00:00Z2019 Aug2026-05-02T19:35:17.746Z2019-08-26T07:03:18ZS-EPMC66983383142167010.1186/s12871-019-0823-6