{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Anstey KJ"],"funding":["Medical Research Council"],"pagination":["S165-S186"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6700718"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["70(s1)"],"pubmed_abstract":["<h4>Background</h4>The translation of evidence on dementia risk factors into clinical advice requires careful evaluation of the methodology and scope of data from which risk estimates are obtained.<h4>Objective</h4>To evaluate the quantity, quality, and representativeness of evidence, we conducted a review of reviews of risk factors for Alzheimer's disease (AD), Vascular dementia (VaD), and Any Dementia.<h4>Methods</h4>PubMed, Cochrane library, and the Global Index Medicus were searched to identify meta-analyses of observational studies of risk factors for AD, VaD, and Any Dementia. PROSPERO CRD42017053920.<h4>Results</h4>Meta-analysis data were available for 34 risk factors for AD, 26 risk factors for Any Dementia and eight for VaD. Quality of evidence varied greatly in terms of the numbe"],"journal":["Journal of Alzheimer's disease : JAD"],"pubmed_title":["A Systematic Review of Meta-Analyses that Evaluate Risk Factors for Dementia to Evaluate the Quantity, Quality, and Global Representativeness of Evidence."],"pmcid":["PMC6700718"],"funding_grant_id":["G0500997","MR/J50001X/1"],"pubmed_authors":["Peters R","Jagger C","Anstey KJ","Eramudugolla R","Ee N"],"additional_accession":[]},"is_claimable":false,"name":"A Systematic Review of Meta-Analyses that Evaluate Risk Factors for Dementia to Evaluate the Quantity, Quality, and Global Representativeness of Evidence.","description":"<h4>Background</h4>The translation of evidence on dementia risk factors into clinical advice requires careful evaluation of the methodology and scope of data from which risk estimates are obtained.<h4>Objective</h4>To evaluate the quantity, quality, and representativeness of evidence, we conducted a review of reviews of risk factors for Alzheimer's disease (AD), Vascular dementia (VaD), and Any Dementia.<h4>Methods</h4>PubMed, Cochrane library, and the Global Index Medicus were searched to identify meta-analyses of observational studies of risk factors for AD, VaD, and Any Dementia. PROSPERO CRD42017053920.<h4>Results</h4>Meta-analysis data were available for 34 risk factors for AD, 26 risk factors for Any Dementia and eight for VaD. Quality of evidence varied greatly in terms of the numbe","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019","modification":"2026-05-07T08:45:17.556Z","creation":"2019-09-07T07:01:17Z"},"accession":"S-EPMC6700718","cross_references":{"pubmed":["31306123"],"doi":["10.3233/JAD-190181"]}}